July 2012 in “Medical Hypotheses” Artemis dysfunction might cause hair loss through telomere shortening.
1 citations
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April 2015 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” Skin and hair aging involves mitochondrial issues, telomere shortening, and hormonal changes, with iron affecting hair loss in pre-menopausal women.
January 2013 in “edoc (University of Basel)” TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.
64 citations
,
November 2012 in “EMBO reports” Lamins are vital for cell survival, organ development, and preventing premature aging.
414 citations
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August 2005 in “Nature” Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
9 citations
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May 2021 in “Frontiers in aging neuroscience” Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Activating telomerase can boost hair follicle stem cell growth and hair production.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
7 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
April 2020 in “The FASEB Journal” Loss of Rap1 protein speeds up heart aging in mice.
3 citations
,
August 2012 in “Nature Cell Biology” Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
2 citations
,
December 2011 in “Annales de Dermatologie et de Vénéréologie” 2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
August 2007 in “Journal of Investigative Dermatology” The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.
20 citations
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January 2021 in “GeroScience” Spermidine helps protect against aging by preserving telomere length.
11 citations
,
January 2000 in “Journal of Cutaneous Pathology” Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
19 citations
,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
32 citations
,
February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
5 citations
,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
April 2022 in “Research Square (Research Square)” Researchers created a stable rabbit cell line for hair research that doesn't age quickly or become cancerous.
36 citations
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September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
August 2012 in “Nature Cell Biology” A pathway helps maintain long telomeres in both stem and cancer cells.
2 citations
,
April 2018 in “Natural Product Communications” Cynomorium songaricum has many health benefits and could help with hair regrowth.
12 citations
,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
1 citations
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January 2025 in “Aging and Disease” Lengthening telomeres may reverse aging and extend lifespan.
77 citations
,
July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
70 citations
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March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
30 citations
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September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
26 citations
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July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
20 citations
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January 2015 in “Current problems in dermatology” Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.