research HAIRY PREGNANCY
A woman's increased hair growth during pregnancy due to PCOS resolved after delivery.
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research The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana tropicalis
Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
research Dermatologic Implications of Glycemic Control Medications for Patients with Type 2 Diabetes Mellitus
Glycemic control medications for Type 2 diabetes can affect skin conditions like psoriasis.
research Diuretics
Diuretics can cause serious side effects and should be used carefully.
research Antiandrogenic progestins for treatment of signs of androgenisation and hormonal contraception
Certain hormone medications can treat symptoms like acne and unwanted hair, regulate periods, and prevent pregnancy in women and teenage girls.
research Studies of the components of an oral contraceptive agent in albino rats. II. Progestogenic component and comparison of effects of the components and the combined agent
High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
research Drug related lipid metabolism abnormalities: a real-world pharmacovigilance exploratory analysis based on U.S. FDA adverse event reporting system (FAERS)
Many drugs can cause lipid metabolism issues, and labels need better warnings.
research Risk assessment of the top 60 drugs for drug-related sexual dysfunction: a disproportion analysis from the Food and Drug Administration adverse event reporting system
Finasteride, dutasteride, and silodosin have the highest risk for causing sexual dysfunction.
research Use of metformin in pediatric age
Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
research Topical sulfonylurea as a novel therapy for hypertrichosis secondary to diazoxide, and potentially for other conditions with excess hair growth
Topical sulfonylurea may reduce excessive hair growth caused by certain medications.
research Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors
Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.
research Hair care product use among pregnant women of color: protocol for a feasibility educational intervention
Educational efforts can reduce harmful chemical exposure from hair products in pregnant Women of Color.
research Drug-induced vitiligo: a real-world pharmacovigilance analysis of the FAERS database
Certain drugs may cause vitiligo, so patients should be monitored.
research Melatonin supplement induced the hair follicle development in offspring rex rabbits
Melatonin given to pregnant rabbits improved their babies' fur quality.
research Uterus Hyperplasia and Increased Carcinogen-Induced Tumorigenesis in Mice Carrying a Targeted Mutation of the Chk2 Phosphorylation Site in Brca1
Mice with a specific BRCA1 mutation have a higher risk of tumors, especially in the uterus and ovaries.
research Screening of drugs with potential antifungal activity for repurposing in the treatment of cryptococcosis.
Certain antiparasitics and antidepressants show promise for treating cryptococcosis, especially when combined with fluconazole.
research The Myth of Beneficent Nature: The Risks of Herbal Preparations
Herbal products can be dangerous and cause serious health issues.
research Pharmacotherapy of polycystic ovary syndrome - an update
New treatments for PCOS show promise, but no current medication treats all aspects of the condition.
research Monilethrix treated with the oral retinoid Ro 10-9359 (Tigason)
Tigason improved hair growth in a boy with monilethrix without side effects.
research Finasteride in the treatment of men with androgenetic alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research Hormonal therapies for acne
Hormonal treatments can improve acne, but they come with potential side effects and risks.
research Suppression of spermatogenesis with desogestrel and testosterone pellets is not enhanced by addition of finasteride.
research Ann Robinson’s research reviews —12 May 2022
Self-monitoring blood pressure in pregnant women didn't improve outcomes, diabetes drugs may increase gallbladder disease risk, a new drug helps severe hair loss, a plant-based COVID-19 vaccine is 69.5% effective, and new anticoagulants are safer for diabetics with heart rhythm issues than warfarin.
research Excretion of technetium in human milk
research Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices
Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
research Methotrexate for induction of remission in ulcerative colitis
Methotrexate is not proven effective for inducing remission in ulcerative colitis.
research Prace poglądowe Folate supplementation in patients with psoriasis treated with methotrexate – effect on safety and efficacy
Folate may reduce methotrexate side effects in psoriasis patients, but its impact on effectiveness is unclear.
research Nėštumas sergant policistinių kiaušidžių sindromu: literatūros apžvalga
PCOS increases risks of gestational diabetes, hypertension, and caesarian deliveries in pregnancy.
research Trends in the presence or absence of transaminitis and/or leukopenia in pediatric patients treated with methotrexate for inflammatory skin disease
Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.
research Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.