Search

everythinglearnresearchcommunity

for

Search:↓

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

Cortisol increases a specific protein in bone cells, which may help explain its negative effects on bone.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Body hair isn't a good substitute for scalp hair in steroid analysis.

Quercetin may help with PCOS symptoms, but more research is needed.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.

Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.

Clomiphene citrate can reverse low hormone levels and symptoms in male runners with hypogonadotropic hypogonadism.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Zinc deficiency in male goats leads to poor hair growth, smaller testicles, reduced libido, and is hard to reverse.

About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.