13 citations
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December 2017 in “CNS Neuroscience & Therapeutics” Finasteride affects young male rats' brain function and behavior negatively.
13 citations
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January 2016 in “Journal of cosmetology & trichology” Alternative treatments show promise for hair growth beyond traditional methods.
13 citations
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August 1995 in “The Journal of Steroid Biochemistry and Molecular Biology” The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
13 citations
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January 1995 in “Postgraduate medicine” Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.
13 citations
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June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
12 citations
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January 2020 in “touchREVIEWS in Endocrinology” Testosterone may both worsen and protect against COVID-19 effects in men.
12 citations
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October 2004 in “Experimental Gerontology” Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
11 citations
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March 2019 in “Journal of The American Academy of Dermatology” Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.
11 citations
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December 2010 in “The Journal of Urology” Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
11 citations
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August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
10 citations
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February 2020 in “Endocrine” Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
10 citations
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February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
10 citations
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May 2009 in “Cases Journal” A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
10 citations
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May 2009 in “Sexual and Relationship Therapy” The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
9 citations
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January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
9 citations
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January 2016 in “Skin Pharmacology and Physiology” The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
9 citations
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September 2014 in “Cancer Epidemiology, Biomarkers & Prevention” Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.
8 citations
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December 2017 in “Cancer Medicine” Finasteride use may increase the risk of male breast cancer.
8 citations
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May 1996 in “Endocrinology” Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
8 citations
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January 1996 in “Gynecological Endocrinology” Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
8 citations
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October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
7 citations
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December 2019 in “American Journal of Clinical Dermatology” Topical therapies show promise for hair loss and acne treatment with minimal side effects.
7 citations
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March 2011 in “Expert Opinion on Drug Safety” Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
6 citations
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January 2013 Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
6 citations
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November 2010 in “International Journal of Andrology” New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
5 citations
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April 2021 in “Journal of Endocrinological Investigation” Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
5 citations
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February 2019 in “Oral and Maxillofacial Surgery” Hair loss can be reversed or even cured using advanced hair restoration techniques, with rare complications like swelling and bleeding.
5 citations
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November 1992 in “Current problems in dermatology” Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
4 citations
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October 2022 in “Evidence-based complementary and alternative medicine” Ficus carica extract improved fertility in rats and may help with certain health conditions.
4 citations
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January 2021 in “Journal of Clinical Medical Research” c-Kit is important for heart regeneration and cancer development.