research Manifestation of Hyperandrogenism in the Continuous Light Exposure-Induced PCOS Rat Model
Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
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research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia
Finasteride effectively treats BPH but may increase sexual dysfunction risk.
research Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human
Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
research The influence of androgens on insulin resistance
Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
research Androgenetic alopecia and microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research No evidence for the immunocompetence handicap hypothesis in male humans
Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
research Adverse effects of common medications on male fertility
Some common medications can harm male fertility, but many effects can be reversed.
research Male gonadal function in coeliac disease: 2. Sex hormones.
Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.
research The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia
Finasteride effectively reduces hair loss by decreasing androgen levels.
research 3α-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats
3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research Established risk factors for coronary heart disease are unrelated to androgen-induced baldness in female-to-male transsexuals
Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.
research 6 Peripheral androgens and the role of androstanediol glucuronide
Androstanediol glucuronide is a reliable marker for hirsutism in women.
research Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone
Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Increased Androgen Binding Capacity in Sebaceous Glands in Scalp of Male-pattern Baldness
Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.
research The effect of spironolactone on genital skin 5α-reductase activity
Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
research Endophytes in Southeast Asia and Japan: their taxonomic diversity and potential applications
Endophytes from Southeast Asia and Japan can produce useful substances like enzymes and antibiotics.
research A Comparison of the Hormonal Profile of Early Androgenetic Alopecia in Men With the Phenotypic Equivalent of Polycystic Ovarian Syndrome in Women
Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.
research Ketoconazole Therapy for Women with Acne and/or Hirsutism
Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
research Anabolic effects of testosterone are preserved during inhibition of 5α-reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
research Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats
Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
research Finasteride versus cyproterone acetate-estrogen regimens in the treatment of hirsutism
Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
research Role of testosterone in SARS-CoV-2 infection: A key pathogenic factor and a biomarker for severe pneumonia
Low testosterone may indicate severe COVID-19 in men.
research Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents
Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
research Metformin influence on hormone levels at birth, in PCOS mothers and their newborns
Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
research Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp
Minoxidil boosts enzymes that help hair growth.
research Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia
Finasteride effectively treats male hair loss, improving growth and density.