29 citations
,
September 1983 in “British Journal of Dermatology” Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.
4 citations
,
August 2024 in “PLoS ONE” Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.
1 citations
,
January 2023 in “Journal of Obstetrics and Gynaecology” High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.
March 2024 in “BMC women's health” The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
November 1986 in “PubMed” Women with androgenetic alopecia have lower SHBG levels.
29 citations
,
January 2006 in “Clinical chemistry and laboratory medicine” SHBG binding properties are unchanged in male liver cirrhosis patients.
40 citations
,
March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
53 citations
,
January 1985 in “Acta obstetricia et gynecologica Scandinavica” Low-dose oral contraceptives reduced hair growth and testosterone levels in women with polycystic ovary syndrome.
24 citations
,
November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
15 citations
,
August 2010 in “Fertility and sterility” Metformin works better for adolescent girls with PCOS who have certain genetic variations.
August 1987 in “European journal of endocrinology” The T/SHBG ratio may be a useful marker for androgen activity in women with androgenetic alopecia.
42 citations
,
July 1982 in “PubMed” Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.
Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.
18 citations
,
May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
15 citations
,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
11 citations
,
December 2010 in “The Journal of Urology” Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
7 citations
,
May 2012 in “International Journal of Andrology” The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
6 citations
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January 2019 in “F1000Research” High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
2 citations
,
April 2023 in “Pharmaceuticals” Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
2 citations
,
January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
February 2025 in “East African Scholars Journal of Medical Sciences” Higher testosterone and DHEA-S levels may be linked to male pattern baldness.
March 2015 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Testosterone affects skin by increasing oil production and influences hair growth.
The oral testosterone effectively increased testosterone levels and reduced SHBG, showing promise for treating testosterone deficiency.
November 2017 in “Reactions Weekly” Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.
15 citations
,
September 1973 in “PubMed” High androgen levels often cause female hirsutism and infertility.
January 2016 in “Renal Failure” Kidney stones and hair loss are significantly related in people under 60 years old.
197 citations
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January 2019 in “Neuropsychopharmacology” Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
5 citations
,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
20 citations
,
December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.