research A Review on Finasteride: A 5-Alpha Reductase Inhibitors, its Mechanism, Facts and Benefits
Finasteride effectively treats hair loss and prostate issues with minimal side effects.
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research Finasteride as a Neo-Adjuvant Treatment for TURPLiterature Review
Finasteride, a drug that prevents testosterone conversion, can effectively reduce blood loss in prostate surgery, especially for patients with a prostatic volume over 30 cc, and decrease post-surgery complications.
research Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives.
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research Contemporary medical therapy for polycystic ovary syndrome
New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
research Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal papilla cells
Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
research Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Re-growth in Testosterone-treated Mice
Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
research Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Testosterone up-regulates vacuolar ATPase expression and functional activities in vas deferens of orchidectomized rats
Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
research Modulating testosterone pathway: a new strategy to tackle male skin aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
research Effect of Citrullus colocynthis Schard on Testosterone-Induced Benign Prostatic Hyperplasia
Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
research Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone
Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.
research Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line
Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
research Hair growth promoting effect of white wax and policosanol from white wax on the mouse model of testosterone-induced hair loss
White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
research Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection
Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
research Increase in testosterone metabolism in the rat central nervous system by formalin-induced tonic pain
Formalin-induced pain increases testosterone breakdown in the rat brain and spinal cord.
research Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats
Agomelatine may help reduce benign prostatic hyperplasia by blocking certain inflammatory pathways.
research Effect of Fenugreek Extract on Testosterone Propionate-Induced Benign Prostatic Hyperplasia
Fenugreek extract may help treat benign prostatic hyperplasia.
research The In Vivo and In Vitro Effects of Terminalia bellirica (Gaertn.) Roxb. Fruit Extract on Testosterone-Induced Hair Loss
Terminalia bellirica extract may help promote hair growth and prevent hair loss caused by testosterone.
research 013 Prostaglandin D2 enhances testosterone metabolism by ROS-mediated altered redox potential in keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
research Efectos de la terapia combinada del D-004 y el Finasteride sobre la hiperplasia de próstata inducida por testosterona en ratas
Combining D-004 and finasteride is more effective at reducing prostate enlargement than using either alone.
research Zhuangyao Jianshen pill ameliorates testosterone-induced benign postatic hyperplasia in rats.
Zhuangyao Jianshen pill reduces prostate enlargement and inflammation in rats.
research Administration Of 45% Robusta (Coffea canephora) Green Coffee Bean Ethanol Extract Solution Could Not Increased Hair Growth But Inhibited The Increase Of 5α-Reductase Type 1 Levels In Male Wistar Rats (Rattus norvegicus) Exposed To Topical Testosterone
Green coffee bean extract didn't grow hair but reduced a hair loss-related enzyme in rats.
research Intracrine testosterone activation in human pancreatic β cells stimulates insulin secretion.
Testosterone in human pancreas cells boosts insulin production.
research Compounded Testosterone Troches TO OPTIMIZE HEALTH AND THE TESTOSTERONE CONTROVERSY.
Properly administered testosterone therapy is safe and effective but often not covered by insurance.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Preparation of3H-labelled testosterone metabolites
The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Physcion, a novel inhibitor of 5α-reductase that promotes hair growth in vitro and in vivo
Physcion may help treat hair loss by blocking an enzyme linked to baldness.
research Faculty Opinions recommendation of Association between 5-alpha reductase inhibition and risk of hip fracture.
5-alpha reductase inhibitors do not increase hip fracture risk.