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Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.

The effect of GLP-1 RAs on erectile function is unclear and needs more research.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

Adding bentonite clays to goat diets increased milk yield, periwinkle shell improved chicken egg production, and vaccination increased muscle area and carcass yield in calves.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Compound 15a was effective in inhibiting 5α-reductase.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Androgens in female meerkats influence aggression and dominance, affecting social dynamics and offspring behavior.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Green algae can break down finasteride, reducing environmental harm.

Finasteride may negatively affect male fertility.