March 2024 in “Romanian Medical Journal” Inositol shows promise in treating PCOS and other health issues, but more research is needed.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
49 citations
,
May 2018 in “Endocrine” Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.
21 citations
,
November 2017 in “Archives of Dermatological Research” Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
9 citations
,
January 2014 in “Medical Hypotheses” Higher DHT in male baldness may protect against prostate cancer.
7 citations
,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
7 citations
,
July 2019 in “Scientific Reports” Finasteride helps reduce heart enlargement in heart failure patients.
56 citations
,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
108 citations
,
February 2008 in “The Journal of urology/The journal of urology” Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
97 citations
,
April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
72 citations
,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
71 citations
,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
68 citations
,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
51 citations
,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
41 citations
,
September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
38 citations
,
June 2015 in “Expert Opinion on Therapeutic Targets” Blocking the prolactin receptor might help treat various diseases, but more research is needed.
38 citations
,
September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
32 citations
,
January 2007 in “Biological & Pharmaceutical Bulletin” Minoxidil and retinol together help hair grow.
22 citations
,
November 2024 in “Planta” Aromatic plants can naturally help prevent skin aging and improve skin health.
21 citations
,
May 2021 in “Prostate Cancer and Prostatic Diseases” COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
20 citations
,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
19 citations
,
August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
18 citations
,
August 2019 in “Drug Development and Industrial Pharmacy” Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.
18 citations
,
March 2009 in “Medical Hypotheses” The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
16 citations
,
June 2021 in “Journal of Dermatological Treatment” Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.
14 citations
,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
13 citations
,
June 2024 in “Asian Pacific Journal of Cancer Prevention” The (+) enantiomer of YH239-EE effectively kills breast cancer cells.
10 citations
,
February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
8 citations
,
July 2018 in “Current Sexual Health Reports” Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.