78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
77 citations
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October 1986 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.
76 citations
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December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
76 citations
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November 1997 in “The American journal of psychiatry” Some autistic children may have higher levels of male hormones, which could be linked to aggression.
73 citations
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June 2008 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
71 citations
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July 2015 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
66 citations
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November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
66 citations
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October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.
60 citations
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July 2018 in “Circulation” Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.
59 citations
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
research ACNE
58 citations
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January 1997 in “Dermatologic Clinics” Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
58 citations
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July 1974 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.
56 citations
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October 2018 in “Journal of The American Academy of Dermatology” Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
50 citations
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April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
49 citations
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September 1986 in “British Journal of Dermatology” Hidradenitis suppurativa improves with antiandrogen therapy.
48 citations
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February 2008 in “Nutrition in Clinical Practice” Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
46 citations
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August 2022 in “Journal of Endocrinological Investigation” COVID-19 temporarily affects male reproductive health, but sperm and testosterone levels generally return to normal after three months.
46 citations
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July 1974 in “The Journal of Clinical Endocrinology & Metabolism” Low estrogen and high testosterone may cause excessive hair growth in women.
44 citations
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January 2008 in “Fertility and Sterility” Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.
43 citations
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July 1984 in “Clinical and Experimental Dermatology” Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
43 citations
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May 1988 in “British Journal of Dermatology” Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
40 citations
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January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
39 citations
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August 2001 in “Clinical endocrinology” Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.
36 citations
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June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
36 citations
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November 2009 in “European Radiology” The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.
31 citations
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February 1997 in “The Journal of Clinical Endocrinology and Metabolism” People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.
30 citations
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April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry” Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.
28 citations
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November 2019 in “Frontiers in Endocrinology” Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.
28 citations
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November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The normal human prostate does not significantly affect blood DHT levels.
27 citations
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May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.