15 citations
,
February 2013 in “Pharmaceutical nanotechnology” Finasteride delivery through skin improved using invasomes and iontophoresis.
12 citations
,
September 2018 in “Journal of Drug Delivery Science and Technology” The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.
11 citations
,
March 2016 in “Translational Andrology and Urology” Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
September 2023 in “Biology of reproduction” New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
December 2016 in “The Journal of Sexual Medicine” Short-acting testosterone injections in a clinic are a preferred treatment for low testosterone because they work well, are convenient, and patients stick with the treatment.
March 2004 in “Current Sexual Health Reports” Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
31 citations
,
January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
October 2022 in “Endocrine journal” Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.
30 citations
,
March 2016 in “European Journal of Pharmaceutical Sciences” Optimized film improves finasteride skin absorption and treatment efficiency.
1 citations
,
June 2008 in “The Journal of Urology” Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.
28 citations
,
March 2014 in “International Journal of Nanomedicine” New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.
Testosterone pellets may help women's sexual function but have safety concerns and need more research.
33 citations
,
January 2013 in “Dermatology” Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
146 citations
,
December 2016 in “Translational Andrology and Urology” Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.
46 citations
,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
32 citations
,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
13 citations
,
January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
1 citations
,
January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
November 2023 in “JAAD case reports” Exogenous testosterone use may be linked to developing hidradenitis suppurativa.
May 2023 in “Journal of drugs in dermatology” Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.
April 2023 in “International Journal of Pharmaceutics” Melatonin in a special emulsion can help treat hair loss more effectively.
3 citations
,
August 2004 in “International journal of gynaecology and obstetrics” Finasteride doesn't change polycystic ovary size or cyst number, suggesting testosterone's role in their appearance.
January 2014 in “Revista del Centro Dermatológico Pascua” Male pattern baldness is not a risk factor for heart disease based on cholesterol levels alone.
34 citations
,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
28 citations
,
October 2018 in “Clinical Obstetrics and Gynecology” Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
16 citations
,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
1 citations
,
December 2010 in “Elsevier eBooks” Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
658 citations
,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
282 citations
,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
237 citations
,
January 2010 in “The Journal of Sexual Medicine” The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.