research Klinefelter syndrome and chronic leg ulcers
A man with Klinefelter syndrome had a leg ulcer that didn't heal well, even with treatment.
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330-360 / 1000+ results research Androgen action on human skin – from basic research to clinical significance
Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
research Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism
Key enzymes control androgen levels, affecting hormone activity and potential treatments.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research Inflammatory perspectives of polycystic ovary syndrome: role of specific mediators and markers
PCOS is linked to inflammation, and certain markers could help in its treatment.
research Characteristics of flutamide action on prostatic and testicular functions in the rat
Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
research Age-dependent endocrine disorders involved in the pathogenesis of refractory acne in women
Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.
research Effects of finasteride, a 5 alpha-reductase inhibitor, on circulating androgens and gonadotropin secretion in hirsute women.
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Skin diseases in consequence of endocrine alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research Medicolegal aspects of doping in football
Doping in football faces legal challenges with testosterone limits, hair loss treatments, and recreational drug use.
research Hyperandrogénie féminine
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research A Case of Familial Male-limited Precocious Puberty with a Novel Mutation
A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research Female pattern hair loss in men: A distinct clinical variant of androgenetic alopecia
Men can experience female pattern hair loss, needing different treatments.
research Rational investigations in the diagnosis and management of women with hirsutism or androgenetic alopecia
Diagnose and manage hair issues in women by checking medical conditions and using personalized treatments.
research Theoretical Evaluation of Twenty-Cannabinoid Derivatives on Either Androgen Receptor or 5α-Reductase Enzyme
Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.
research Mechanism of androgenic alopecia: Addressing speculations through empirical evidences
Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
research Exploring the clinical implications of novel SRD5A2 variants in 46,XY disorders of sex development
New SRD5A2 variants may disrupt protein function, aiding diagnosis and treatment of related disorders.
research Alopecia and Clinical Presentation of Endocrinopathies: Pathogenetic and Diagnostic Aspects
Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
research Androgenetische Alopezie beim Mann . Male androgenetic alopecia
Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
research Androgenic Alopecia: Recent Understanding of the Androgenetic Receptor-Mediated Molecular Mechanisms and Current Pharmacotherapy
Androgenic alopecia is mainly caused by DHT, and new treatments focus on hair regeneration and aging factors.
research Insulin Resistance in an Underweight Woman with Polycystic Ovary Syndrome: A Case Study
Underweight women with PCOS can have insulin resistance, and treatment with metformin and dexamethasone can improve symptoms.
research Ovarian hyperthecosis in adolescent females: two case reports and a review of the literature
Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.
research Formulation and In-vivo Assessment of Topical Polyherbal Hair Serum to Promote Hair Growth
The polyherbal hair serum helped prevent hair loss and improved hair growth better than the usual treatment.
research Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature
A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.
research Development and evaluation of finasteride niosomes targeting to hair follicles for the management of androgenic alopecia
Finasteride niosomes were developed and found to be effective in treating hair loss, with better results than commercial minoxidil, and could be a promising topical treatment for hair loss.
research Investigation of follicle stimulating effect of medical cosmetic remedies on the androgen alopecia model in rats
The cream-mask and gel-mask with certain plant extracts improved hair growth in rats similar to a common hair growth treatment.
research Андрогенетическая алопеция: патогенетические механизмы и подходы к лечению
Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.
research Pattern alopecia in a miniature pinscher dog
A Miniature Pinscher dog with hair loss and scaling was diagnosed with pattern alopecia and improved with melatonin treatment.