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research Endocrine care of transpeople part I. A review of cross-sex hormonal treatments, outcomes and adverse effects in transmen

45 citations , March 2015 in “Clinical Endocrinology”

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

research Gonadal dysgenesis and bone metabolism

45 citations , February 2001 in “Joint bone spine”

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

research Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb.

44 citations , March 2012 in “Fitoterapia”

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

research Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia

44 citations , January 2012 in “Food and chemical toxicology”

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

research Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome

44 citations , January 2008 in “Fertility and Sterility”

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

research Genetic Analysis of Androgen Receptors in Development and Disease

44 citations , January 1999 in “Advances in pharmacology”

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

research Solubilizing steroidal drugs by β-cyclodextrin derivatives

43 citations , July 2017 in “International journal of pharmaceutics”

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

research Hormonal status of male reproductive system: androgens and estrogens in the testis and epididymis. In vivo and in vitro approaches.

43 citations , January 2006 in “PubMed”

Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.

research A Review of Androgen‐Progestin Regimens for Male Contraception

43 citations , July 2003 in “Andrology”

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

research Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil).

43 citations , January 1999 in “Endocrinology”

Cortisol increases a specific protein in bone cells, which may help explain its negative effects on bone.

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