110 citations
,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
52 citations
,
August 2021 in “Microorganisms” Higher ACE2 levels in certain tissues may worsen COVID-19 in people with other health issues, especially older adults.
5 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
124 citations
,
October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
55 citations
,
July 2016 in “Dermatologic Therapy” Multiple treatments work best for hair loss.
258 citations
,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
180 citations
,
January 2003 in “American Journal of Clinical Dermatology” Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
171 citations
,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
135 citations
,
December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
119 citations
,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.
28 citations
,
March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
28 citations
,
January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
24 citations
,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
23 citations
,
October 2018 in “Australasian Journal of Dermatology” The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
16 citations
,
July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
15 citations
,
August 2006 in “Journal of Cutaneous Pathology” HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
7 citations
,
September 2022 in “International journal of molecular sciences” The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.
5 citations
,
January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
3 citations
,
June 2021 in “Cosmetics” A mix of sulforaphane, L-menthol, and dexpanthenol could help increase hair growth and reduce hair loss.
July 2019 in “Journal of Investigative Dermatology” The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
October 2018 in “InTech eBooks” The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
January 2017 in “Brazilian Journal of Pharmaceutical Sciences” Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
139 citations
,
May 2020 in “Stem Cell Research & Therapy” Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
1 citations
,
March 2018 in “Dermatologie pro praxi” Most over-the-counter hair loss treatments lack strong evidence of effectiveness, except for minoxidil, which works but stops working if you stop using it.
December 2015 in “Vascular Pharmacology” Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
375 citations
,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
144 citations
,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
138 citations
,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.