146 citations
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July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
141 citations
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August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
137 citations
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June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
136 citations
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April 2016 in “Dermatologic Surgery” PRP treatment helps hair growth and density in androgenetic alopecia patients.
135 citations
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December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
120 citations
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October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
82 citations
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October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
74 citations
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September 2006 in “Cell Cycle” The HR protein's role as a repressor is essential for controlling hair growth.
64 citations
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July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
64 citations
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August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
51 citations
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July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
47 citations
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March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
42 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
38 citations
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June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
32 citations
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January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
30 citations
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September 2017 in “Clinics in Dermatology” Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
30 citations
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July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
28 citations
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November 2019 in “Gene” The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
27 citations
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June 2015 in “Revista Brasileira de Farmacognosia” Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.
25 citations
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April 2018 in “Journal of Cosmetic Dermatology” PRP injections increase hair density and diameter in female androgenetic alopecia patients.
24 citations
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December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
20 citations
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January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
18 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Lasers, microneedling, and PRP improve skin rejuvenation and repair, with PRP enhancing the effects when combined with other treatments.
16 citations
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July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
14 citations
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April 2020 in “Journal of Cosmetic Dermatology” QR678 treatments were more effective and comfortable for male hair loss than PRP treatments.
11 citations
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August 2019 in “Journal of Molecular Histology” NFIC helps rat dental cells grow and turn into bone-like cells.
9 citations
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December 2013 in “Toxicological Research” Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
2 citations
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April 2022 in “Clinical, cosmetic and investigational dermatology” A new plant-based treatment was effective for hair regrowth in women with a specific type of hair loss that didn't respond to usual treatments.
2 citations
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November 2017 in “Journal of Cosmetic Dermatology” Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.