28 citations
,
August 2005 in “Journal of Investigative Dermatology” TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.
August 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF18 controls hair cycle rest and growth phases.
9 citations
,
August 2024 in “Tissue Engineering and Regenerative Medicine” Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
April 2018 in “Journal of Investigative Dermatology” Fgf20 is important for the development and regulation of the cells that form the base of hair follicles.
101 citations
,
November 2011 in “Nature Communications” Wnt/β-catenin signaling is crucial for cell fusion in placental development.
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
24 citations
,
November 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.
25 citations
,
June 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
Lack of Fgf21 slows hair growth by affecting gene interactions.
4 citations
,
September 2024 in “Development” Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.
July 2025 in “Journal of Investigative Dermatology” Wnt and SHH pathways help form hair follicles by coordinating cell processes.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.
12 citations
,
June 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Activating TRPV3 channels stops hair growth by killing hair follicle cells.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
3 citations
,
December 2024 in “Journal of Animal Physiology and Animal Nutrition” FGF20 is essential for hair follicle stem cell growth and development in fine-wool sheep.
5 citations
,
March 1993 in “The Journal of Cell Biology” A soluble factor in developing mouse whisker pads boosts nerve growth factor mRNA production.
158 citations
,
February 2012 in “Journal of Investigative Dermatology” FGF18 helps keep hair in its resting phase, affecting hair growth cycles.
5 citations
,
September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
EGF and FGF signaling stops hair follicle development in mice.
Using Arabidopsis thaliana to produce KGF-2 is a promising, cost-effective method for hair growth and wound healing products.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
25 citations
,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
March 2016 in “Experimental Dermatology” EGFR helps hair follicles transition properly by controlling Stathmin levels.
475 citations
,
October 2006 in “Proceedings of the National Academy of Sciences” Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
January 2024 in “OPAL (Open@LaTrobe) (La Trobe University)” TRPV3 channels are involved in skin processes and are affected by shear stress, influencing itch and mechanotransduction.
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
28 citations
,
January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.