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LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Introducing the OTC gene improved symptoms in mice with OTC deficiency.

A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.

Proteoglycan replacement therapy improved hair conditions in most patients with alopecia.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

TSG from Polygonum multiflorum may help with anti-aging by protecting the brain, heart, bones, and hair.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.

PTHrP regulates various normal body functions, including bone development, skin, and muscle function.

A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

CCC1 is essential for pH balance and normal cell function in plants.

TGF-β1 and 2 may play a role in hair loss in AGA.

Phospholipids help plant proteins move by regulating receptor interactions.

The enzyme is crucial for skin cell development and can be activated without proteolytic activation.

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

Misdiagnosis led to unnecessary treatment due to a genetic mutation affecting thyroid hormone resistance.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

TGF-β1 and 2 in hair follicles may be linked to hair loss in AGA.

A new compound was effective for imaging prostate cancer in rats.

TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.

TRPV3 channels are involved in skin processes and are affected by shear stress, influencing itch and mechanotransduction.

CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.

A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

The new bariatric surgery SAGI PGP is effective for weight loss and diabetes control with few complications.

The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.

Sacituzumab govitecan improves quality of life and symptoms in breast cancer patients, except for causing more diarrhea.