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Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Chromosomal microarray analysis is important for diagnosing rare genetic variations and guiding treatment.

A woman's masculine symptoms were caused by a rare tumor in her left ovary, which was found using a special blood test.

The study found that imaging might miss small ovarian tumors causing high testosterone, and suggested using certain testosterone levels and treatment responses to identify these tumors.

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

The TT genotype of a specific SNP in sheep is linked to better wool quality.

Researchers found a way to make rat hair follicle cells start turning into motor neuron-like cells, but couldn't fully turn them into working motor neurons.

Nonclassic 21-hydroxylase deficiency is a common, treatable genetic disorder causing reversible symptoms like acne and hair loss.

Several genes, including Hox-7A, Stra6, and Lim-1, are involved in normal palate formation.

Leydig cell tumors in the ovary can cause high testosterone and male traits in postmenopausal women but are treatable with surgery.

A 532 nm laser at 15 J/cm2 speeds up tendon healing by increasing tendon stem cell growth and tendon-related gene activity.

Inhibiting TYK2 can restore hair growth in alopecia areata.

Surgery removed an ovarian tumor, improving her symptoms and normalizing testosterone levels.

A specific type of immune cell plays a key role in causing alopecia areata and could be a target for treatment.

Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.

A cluster of 21 keratin-associated protein genes important for hair growth was found on human chromosome 21.

Monilethrix is linked to a gene cluster on chromosome 12.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.

Alopecia areata patients show increased inflammation and OX40 activation, suggesting a new treatment target.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Trichohyalin in hair can trigger immune attacks in alopecia areata.

The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.

DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

Human adrenals and gonads have a unique enzyme for steroid hormone production.

CaV1.2 helps activate hair follicle stem cells without calcium flux.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.