16 citations
,
June 2017 in “JAMA Dermatology” Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.
15 citations
,
January 2014 in “Anais Brasileiros de Dermatologia” Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
November 1990 in “Inpharma weekly” Flutamide effectively treated hair growth and related symptoms in women, with common side effects like dry skin and hot flushes.
24 citations
,
December 2009 in “Future Medicinal Chemistry” Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
February 2020 in “Central Plains Medical Journal” Thalidomide with CHOP is more effective for peripheral T-cell lymphoma than CHOP alone.
64 citations
,
May 2000 in “International Journal of Dermatology” Thalidomide improved lupus symptoms but caused nerve damage in some patients.
130 citations
,
September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
29 citations
,
May 1975 in “Clinical Endocrinology” Combination therapy significantly reduces testosterone and moderately reduces hair growth in women with hirsutism.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
17 citations
,
April 1997 in “Archives of dermatology” The document describes a treatment for excessive hair growth in a teenage girl using medication and birth control, but does not report the results.
74 citations
,
March 2001 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.
18 citations
,
October 2018 in “Journal of The American Academy of Dermatology” Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.
36 citations
,
November 1995 in “Clinical endocrinology” Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
20 citations
,
December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
7 citations
,
April 2012 in “Clinical investigation” Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
3 citations
,
January 2018 in “Frontiers in bioscience” Daily subcutaneous testosterone effectively restores testosterone levels in men.
62 citations
,
December 1995 in “The Journal of Clinical Endocrinology & Metabolism” Combining a GnRH agonist with a low-dose oral contraceptive is more effective and safer for treating hirsutism than using either alone.
9 citations
,
April 2021 in “Climacteric” Testosterone therapy is effective and safe for women with low sexual desire, but it's hard to access.
2 citations
,
December 2020 in “American Journal of Dermatological Research and Reviews” The combination therapy was effective and well-tolerated, especially in young patients.
34 citations
,
October 2018 in “Journal of The American Academy of Dermatology” Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
February 2016 in “PubMed” Properly administered testosterone therapy is safe and effective but often not covered by insurance.
48 citations
,
January 2005 in “Treatments in Endocrinology”
33 citations
,
January 2009 in “Contraception” Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
20 citations
,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
January 2026 in “Endocrinology”
September 2018 in “The Journal of Urology” Clomiphene citrate is a cheap and simple treatment for low testosterone that works as well as human chorionic gonadotropin, alone or combined, especially for men who want to keep their fertility.
39 citations
,
January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
April 2019 in “Journal of the Endocrine Society” A woman's severe insulin resistance improved with treatment, but she still had high testosterone levels due to ovarian issues.