April 2024 in “Archives of toxicology” Certain substances can protect against ear damage from some antibiotics in zebrafish.
August 2025 in “Journal of Investigative Dermatology” Elevated luteinizing hormone contributes to female-pattern hair loss, and blocking certain channels may help prevent it.
April 2025 in “Journal of Investigative Dermatology” High LH levels cause hair loss by damaging and aging hair follicles.
13 citations
,
August 2021 in “Frontiers in Aging Neuroscience” Hearing decline in SAMP8 mice starts before outer hair cell loss and may be linked to other changes.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
4 citations
,
September 2013 in “Journal of biomolecular structure and dynamics/Journal of biomolecular structure & dynamics” Caribine from traditional Chinese medicine may help treat hair loss.
1 citations
,
October 2022 in “JAAD case reports” Low-dose oral minoxidil can cause serious heart complications.
124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
6 citations
,
October 2022 in “Frontiers in Physiology” Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
4 citations
,
January 2022 in “Journal of Bioscience and Bioengineering” Electric stimulation can increase hair growth by activating certain genes in skin cells.
2 citations
,
May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
397 citations
,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
119 citations
,
June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
3 citations
,
August 2025 in “Cell” Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
February 2024 in “Frontiers in physics” The new model detects hair clusters more accurately and efficiently, helping with early hair loss treatment and diagnosis.
Mealworm extract may help prevent hair loss and promote hair growth due to its antioxidant activity.
November 2025 in “Biomedicine & Pharmacotherapy” Calcium blockers may help prevent hearing loss by protecting hair cells.
January 2023 in “Advances in reproductive sciences” Higher levels of the protein Pannexin-1 may play a role in hair loss in women with PCOS.
November 2010 in “Bradford Scholars (University of Bradford)” KATP channels are crucial for hair growth, and targeting them may lead to new hair loss treatments.
77 citations
,
September 2017 in “Journal of Investigative Dermatology” TRPV3 in skin cells causes inflammation and cell death.
47 citations
,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
82 citations
,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
61 citations
,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
36 citations
,
February 2004 in “Veterinary Dermatology” Lymphangiosarcoma was confirmed in cats with specific skin symptoms using a lymphatic marker.
April 2011 in “The FASEB Journal” Amlodipine impairs fertility in male rats by affecting sperm and testicular structure.
January 2025 in “European Journal of Pharmacology” Forsythoside A may help treat hair loss by blocking specific channels.
36 citations
,
November 2011 in “Journal of the European Academy of Dermatology and Venereology” Effective acne scar treatment should use combination therapy based on specific skin changes.
27 citations
,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
102 citations
,
February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
19 citations
,
February 2016 in “Journal of Biological Chemistry” KCNQ potassium channels help control the sensitivity of touch receptors in the skin.