research Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
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research An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles
Silver nanoparticles in gel form can effectively heal wounds.
research Therapeutic Applications of Nanoemulsion Based Drug Delivery Systems: A Review of Patents in Last Two Decades
Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
research Next-Gen Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Therapeutic approach for metabolic disorders and infertility in women with PCOS
Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.
research Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss
PRP injections may improve hair thickness and density in female hair loss patients.
research Therapeutic strategies for treating hair loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research The Therapeutic Use of Topical Minoxidil
Minoxidil effectively treats hair loss, with better results in women.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
research Anti-diabetic activity of Tridax procumbens
Tridax procumbens may help treat diabetes.
research Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells
Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.
research In Vitroandin VivoStructure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research Therapeutic Androgen Receptor Ligands
Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific
Dutasteride and finasteride affect different cell types differently.
research Pigmented contact dermatitis due to therapeutic sensitizer as complication of contact immunotherapy in alopecia areata
Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.
research Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request
The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.
research Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
research Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury
Exosomes from modified stem cells may help treat liver injury.
research Therapeutic Efficacy of a Combination Therapy of Topical 17α-Estradiol and Topical Minoxidil on Female Pattern Hair Loss: A Noncomparative, Retrospective Evaluation
Combination of 17α-estradiol and minoxidil improves hair growth and reduces hair loss in most patients.
research Therapeutic potential of Sertoli cells in vivo: alleviation of acute inflammation and improvement of sperm quality
Sertoli cell transplants can reduce inflammation and improve sperm quality.
research Recent therapeutic developments for acne
New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
research Therapeutic Application of Microsponges-based Drug Delivery Systems
Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.
research Local anti-inflammatory effect and immunomodulatory activity of chitosan-based dressing in skin wound healing: a systematic review
Chitosan-based dressings reduce inflammation and speed up skin wound healing.
research ANTHELMINTIC ACTIVITY OF MUSA PARADISIACA (L.) CV. PUTTABALE
Banana plant extract effectively kills worms.