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Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.

New diabetes tech and therapies improve care for endocrine disorders.

The treatment temporarily improved symptoms of hyperandrogenism in adolescents.

TCDD reduces EGF receptors in the liver, affecting growth and development.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Metformin/dopamine-derived carbon dots help heal bacteria-infected wounds faster.

Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.

A teenage girl's excessive hair growth was caused by a medication for mania, but improved after stopping the medication.

A new compound effectively inhibits human 5α-reductase 1.

Properly administered testosterone therapy is safe and effective but often not covered by insurance.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with PCOS symptoms no matter the patient's initial insulin resistance or weight.

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Calcitriol and metformin together are more effective for treating PCOS and lowering MCP-1 than metformin alone.

A woman with type 2 diabetes developed alopecia areata, suggesting a link between the two autoimmune conditions.

New pyrazole derivatives may help treat hair loss, but more testing is needed.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

The case emphasizes the need for careful screening in children for insulin resistance and related conditions.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.