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research The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity

55 citations , November 2010 in “Journal of Allergy and Clinical Immunology”

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis - eScholarship

January 2015

Retinoids can help treat skin pigmentation disorders by affecting melanin production.

research Characterization of New Members of the Human Type II Keratin Gene Family and a General Evaluation of the Keratin Gene Domain on Chromosome 12q13.13

92 citations , February 2005 in “Journal of Investigative Dermatology”

research Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODC Transgenic Mice

48 citations , June 2000 in “Japanese Journal of Cancer Research”

Dimethylarsinic acid speeds up skin tumor growth in certain mice.

research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis

9 citations , July 2022 in “EMBO molecular medicine”

Blocking certain immune signals can reduce skin damage from radiation therapy.

research Epitopes, avidity and IgG subclasses of tyrosine hydroxylase autoantibodies in vitiligo and alopecia areata patients

7 citations , February 2012 in “British Journal of Dermatology”

TH antibodies in vitiligo and AA patients recognize the same protein parts.

Xenobiotics In Vitro: The Influence of L-Cystine, Pantothenate, and Miliacin on Metabolic and Proliferative Capacity of Keratinocytes

research Xenobiotics in Vitro: The Influence ofL-Cystine, Pantothenat, and Miliacin on Metabolic and Proliferative Capacity of Keratinocytes

9 citations , January 2006 in “Cutaneous and ocular toxicology”

L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.

research Graft versus host disease–like: A new paraneoplastic syndrome

February 2010 in “Journal of The American Academy of Dermatology”

A woman with thymoma developed a rare chronic condition similar to graft versus host disease after surgery.

research Distinct mutations in human basic hair keratins 1 and 6 cause monilethrix: Implications for protein structure and clinical phenotype

January 1999 in “Journal of Investigative Dermatology”

research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells

8 citations , June 2001 in “Journal of Biological Chemistry”

A truncated protein linked to breast cancer may change cell adhesion.

research Different orientation of the incisions: an efficient method to facilitate the implantation process

September 2009 in “Hair transplant forum international”

Changing the direction of cuts can make it easier to put in implants.

research Scanning electron microscopy of ibrutinib-induced hair shaft changes

1 citations , March 2023 in “Anais Brasileiros de Dermatologia”

research A Homozygous Frameshift Mutation in theHOXC13Gene Underlies Pure Hair and Nail Ectodermal Dysplasia in a Syrian Family

30 citations , January 2013 in “Human Mutation”

A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.

research BRAF Inhibitor Dabrafenib in Patients with Metastatic BRAF-Mutant Thyroid Cancer

188 citations , October 2014 in “Thyroid”

Dabrafenib was effective and well tolerated in treating thyroid cancer with a specific mutation.

Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia

4 citations , July 2012 in “Genesis”

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

research Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis

8 citations , September 2022 in “Human genomics”

Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.

research An in vivo method for the detection of somatic mutations at the cellular level in mice

11 citations , February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis”

A new method can detect mutations in mice by observing changes in hair follicle cells.

research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression

176 citations , February 2006 in “Cancer Research”

Patched1 helps prevent tumors by controlling cell growth.

research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling

40 citations , October 2009 in “Journal of Biomedical Nanotechnology”

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.

research Hypotrichosis with juvenile macular dystrophy: a case report with molecular study

January 2018

A new genetic mutation was found causing hair and eye issues in a boy.

research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration

April 2019 in “Journal of Investigative Dermatology”

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier

4 citations , December 2024 in “European Journal of Medicinal Chemistry”

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

research Reply to: The ends of a conundrum?

March 2007 in “Journal of Cell Science”

K10 may not prevent tumors as previously thought and might increase benign tumor risk.

research Thymosin β4 Promotes Dermal Healing

28 citations , January 2016 in “Vitamins and hormones”

Thymosin β4 helps improve skin healing and reduce scarring.

research Kinetic topographical heterogeneity in follicular thyroid neoplasms and growth patterns

8 citations , August 2007 in “Histopathology”

Different growth patterns in thyroid tumors are influenced by where cell growth and death occur.

research Thallium poisoning. Diagnosis may be elusive but alopecia is the clue.

119 citations , June 1993 in “BMJ”

Alopecia is a key indicator of thallium poisoning.

research Pleiotropic effects of the nude mutation.

9 citations , January 1975 in “PubMed”

Nude mice are hairless due to a shared defect affecting both skin and thymus, not just thymic issues.

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

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