161 citations
,
March 1992 in “International Journal of Dermatology” Alopecia areata often starts before age 20, is more common in women, and may have a genetic link with other autoimmune diseases.
144 citations
,
July 2002 in “Clinical and Experimental Dermatology” Telogen effluvium is a common type of hair loss that can resolve on its own or become chronic, with treatment depending on early diagnosis.
134 citations
,
June 2012 in “International Journal of Oral and Maxillofacial Surgery” Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
92 citations
,
January 2013 in “Dermatology” Vitiligo patients often have other health issues, especially thyroid disorders.
85 citations
,
May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
83 citations
,
May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
68 citations
,
April 1965 in “General and Comparative Endocrinology” The pituitary gland controls seasonal fur color changes in weasels.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
67 citations
,
November 2002 in “Journal of The American Academy of Dermatology” The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.
63 citations
,
March 1995 in “International Journal of Dermatology” Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.
63 citations
,
October 1972 in “British Journal of Dermatology” Women with thinning hair have thinner hair strands than women without hair loss.
62 citations
,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
58 citations
,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
57 citations
,
August 1998 in “The journal of small animal practice/Journal of small animal practice” Malassezia-associated dermatitis can cause itching in cats with feline paraneoplastic alopecia.
56 citations
,
March 2017 in “Journal of the American Academy of Dermatology” Alopecia areata patients often have eczema, thyroid issues, vitamin-D deficiency, and anemia.
56 citations
,
January 2013 in “International journal of trichology” Zinc supplements may be needed to treat hair loss in hypothyroidism.
54 citations
,
March 2009 in “BioEssays” Hormones control keratin production in skin and hair.
53 citations
,
June 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Frontal fibrosing alopecia mainly affects postmenopausal women and may be linked to thyroid hormones.
52 citations
,
October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
51 citations
,
January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
50 citations
,
July 1980 in “Archives of Dermatology” Hidden sweat gland tumors might cause hair loss.
48 citations
,
March 1997 in “Veterinary Dermatology” Some cats with sudden hair loss and tiredness might have cancer-related alopecia.
45 citations
,
November 2015 in “Dermatologic Clinics” Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.
41 citations
,
November 2015 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Diphenylcyclopropenone (DPCP) can help regrow hair in many alopecia areata patients but may cause side effects and relapses.
40 citations
,
September 2003 in “Journal of the American Animal Hospital Association” Hypothyroidism in dogs can cause aggression, which can be treated with thyroid therapy.
40 citations
,
March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
38 citations
,
October 1988 in “Clinics in Dermatology” Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.
37 citations
,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
36 citations
,
November 2018 in “American Journal of Clinical Dermatology” Alopecia is linked to various health and mental conditions, impacts life quality, and needs medical attention beyond its cosmetic effects.