Alopecia areata is an autoimmune disease that targets hair follicles.
35 citations
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August 2009 in “Journal of the American Academy of Dermatology” Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.
Nurses play a crucial role in caring for hyperthyroid patients by managing symptoms and educating them and their families.
58 citations
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July 2018 in “Journal of Allergy and Clinical Immunology” Alopecia areata severity is linked to increased TH1 and TH2 activity.
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May 2026 in “Journal of Dermatological Treatment” JAK1 inhibitor may effectively treat alopecia areata when TNF-α inhibitors and corticosteroids fail.
April 2025 in “Apollo Medicine” Alopecia areata is significantly linked to thyroid issues and may worsen with diabetes severity.
May 2009 in “Endocrinologist” Women with thyroid disease are more likely to experience female pattern hair loss, especially if they've had thyroid disease for a long time.
20 citations
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March 2017 in “Journal of cutaneous pathology” Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.
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December 2022 in “Frontiers in Immunology” Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.
7 citations
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July 2023 in “Immunotherapy” Ritlecitinib works well and is safe for treating alopecia areata.
March 2014 in “Journal of The American Academy of Dermatology” TNF-a may not be as involved in certain types of hair loss as previously thought.
10 citations
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August 2016 in “Oxford Medical Case Reports” Tocilizumab therapy may cause skin and hair conditions like halo naevi, vitiligo, and alopecia areata.
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January 2026 in “Frontiers in Endocrinology” Next-generation Treg therapies could help achieve lasting immune tolerance in type 1 diabetes.
64 citations
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August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
October 2022 in “Journal of pharmaceutical negative results” People with Alopecia areata have higher levels of certain T regulatory cells in their blood.
April 2024 in “Research Square” IBD patients treated with TNF antagonists may develop autoimmune alopecia areata, with severe cases less likely to improve.
38 citations
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January 2009 in “Journal of Cutaneous Medicine and Surgery” A woman developed hair loss after starting a treatment with adalimumab, suggesting this medication might cause hair loss.
5 citations
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July 2003 in “Annals of the Rheumatic Diseases” An antibiotic called co-trimoxazole can effectively treat autoimmune diseases.
April 2019 in “Journal of the Endocrine Society” A woman's severe insulin resistance improved with treatment, but she still had high testosterone levels due to ovarian issues.
34 citations
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November 2022 in “Clinical and Experimental Dermatology” People with alopecia areata are more likely to have other immune-related conditions.
75 citations
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June 2005 in “Archives of Dermatology” Etanercept may not prevent alopecia areata from coming back.
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
6 citations
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November 2010 in “Histochemistry and cell biology” The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
8 citations
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June 2012 in “Journal of Crohn s and Colitis” Managing multiple autoimmune diseases in one patient is extremely challenging.
March 2022 in “International Journal of Trichology” Tofacitinib may be effective for treating hair loss caused by alopecia areata that doesn't respond to other treatments.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking TYK2 might be a new way to treat hair loss from alopecia areata.
9 citations
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February 2012 in “Clinical Neurology and Neurosurgery” Dystonia may be part of PAS-4 and linked to immune issues.
18 citations
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July 2013 in “Journal of Leukocyte Biology” Nonimmunogenic forms of keratins K71 and K31 can delay and prevent alopecia areata.
69 citations
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December 2006 in “Archives of dermatology” Adalimumab may cause severe hair loss in some patients.
21 citations
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January 2024 in “Science Immunology” Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.