31 citations
,
November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
11 citations
,
July 1968 in “JAMA” Itching can be an early sign of hyperthyroidism.
22 citations
,
July 2006 in “Annals of The Royal College of Surgeons of England” Hair or fiber wrapped tightly around a toe can lead to serious injury if not treated quickly.
11 citations
,
July 1999 in “Plastic and Reconstructive Surgery” Surgical treatment for cubital tunnel syndrome can be effective using clinical tests without electrodiagnostics.
September 2024 in “Actas Dermo-Sifiliográficas” Trichodynia is a painful scalp condition linked to hair loss and mental health issues, with limited treatment options.
March 2005 in “Journal of The American Academy of Dermatology” Itch is a common symptom in patients with chronic venous insufficiency, often worsening with standing or sitting and occurring mostly in the evening or at night.
21 citations
,
May 2014 in “Toxicological Sciences” Toluene diisocyanate exposure can cause immune sensitization by interacting with proteins in hair follicles and sebaceous glands.
September 2018 in “Gynecology & Obstetrics” Removing hair wrapped around the labia quickly prevents serious tissue damage.
15 citations
,
July 1968 in “JAMA” Severe itching can be an early sign of hyperthyroidism.
3 citations
,
May 2024 in “Cureus” Early detection and removal of hair can prevent damage in hair-thread tourniquet syndrome.
1 citations
,
January 2001 in “PubMed” Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
April 2024 in “Indian dermatology online journal” A rare hair follicle disorder can cause itchy, bluish-black bumps on the body.
September 2025 in “PubMed” Auricular electrostimulation reduces itching in mice.
6 citations
,
January 2015 in “Il Giornale di Chirurgia” Hair tourniquet syndrome can cause serious harm if not treated quickly, especially in infants.
5 citations
,
April 2016 in “The American Journal of Dermatopathology” A tick bite caused temporary hair loss in a man, which is a rare condition that usually gets better within 3 months.
August 2025 in “Scientific Reports” Itchy keloids on the chest are linked to more nerve fibers and substance P.
March 2026 in “Journal of Clinical and Basic Psychosomatics” Tianmeng oral liquid may help with insomnia, anxiety, and depression.
56 citations
,
November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
March 2025 in “Pain Physician” Cooling the skin before injections reduces pain for patients with hair loss.
21 citations
,
July 2005 in “European Journal of Emergency Medicine” Hair-tourniquet syndrome can cause serious toe injuries in infants but can be treated if found early.
August 2022 in “Archives of pediatric surgery” Hair-Thread Tourniquet Syndrome is a rare condition where hair or thread tightly wraps around a child's body part, requiring quick treatment to prevent damage.
November 2013 in “International Journal of Medical and Health Sciences” Doctors often miss Hair Tourniquet Syndrome, which can lead to serious damage if not treated quickly.
70 citations
,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
January 2016 in “International Journal of Medical Research and Health Sciences” People with hair loss conditions like Telogen Effluvium and Alopecia Areata often feel scalp pain and are more likely to have anxiety, but not necessarily depression.
19 citations
,
March 2013 in “Headache The Journal of Head and Face Pain” A woman's headache and hair loss were relieved by Botox injections.
28 citations
,
January 2010 in “Biological & pharmaceutical bulletin” Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.
Botulinum toxin type A reduces itch and inflammation from histamine and may help treat certain skin conditions and hair loss.
March 2024 in “International journal of molecular sciences” taVNS reduces vitiligo symptoms in mice.
142 citations
,
September 2020 in “Journal of neurophysiology” Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
February 2025 in “Journal of Cosmetic Dermatology” Temporary facial blanching can occur after Botulinum toxin injections, but it resolves without discomfort.