April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
April 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
2 citations
,
September 2022 in “Bioscientia medicina” Topical vitamin D is effective in treating vitiligo with few side effects.
127 citations
,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
43 citations
,
March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.
32 citations
,
July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
26 citations
,
December 2011 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
13 citations
,
October 2010 in “Pharmacogenomics” Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
12 citations
,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
6 citations
,
January 2010 in “Springer eBooks” SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
1 citations
,
January 2009 in “Trepo - Institutional Repository of Tampere University” Vitamin D may help regulate cholesterol and influence prostate cancer development.
January 2017 in “Springer eBooks” The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
January 2017 in “Springer eBooks” Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.
3 citations
,
January 2012 in “Wageningen Academic Publishers eBooks” Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
January 2025 in “SKIN The Journal of Cutaneous Medicine” Calcipotriol's effectiveness for treating alopecia areata is unclear and needs more research.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
October 2023 in “Benha Journal of Applied Sciences” Methotrexate and vitamin D3 are potentially more effective and safer than triamcinolone for treating localized alopecia areata.
300 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
277 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
131 citations
,
August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
127 citations
,
March 2016 in “PLoS ONE” Key genes and pathways crucial for hair follicle development in cashmere goats were identified, aiding fleece production improvement.
120 citations
,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
97 citations
,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
89 citations
,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
60 citations
,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
47 citations
,
September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
43 citations
,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
42 citations
,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
42 citations
,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.