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research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research THE TREATMENT OF BPH WITH HYPERTENSION
Terazosin hydrochloride helps with BPH and blood pressure, but not more than the control.
research Effects of Potassium Channel Modulators on the Responses of Mammalian Slowly Adapting Mechanoreceptors
Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.
research Uji Akvitas dan Keamanan Hair Tonic Ekstrak Daun Kembang Sepatu pada Pertumbuhan Rambut Kelinci
The 10% hibiscus leaf extract hair tonic promotes better hair growth than 2% minoxidil but causes eye irritation.
research Nitroxide pharmaceutical development for age-related degeneration and disease
Nitroxide drugs can safely and effectively treat age-related diseases like macular degeneration and cardiovascular issues.
research Clinical Study of Tolterodine Tartrate in the Treatment of Overactive Bladder
Tolterodine Tartrate effectively treats overactive bladder symptoms.
research FORMULASI SEDIAAN HAIR TONIC EKSTRAK ETANOL DAUN TEH HIJAU (Camellia sinensis L.) SEBAGAI PENUMBUH RAMBUT TERHADAP KELINCI JANTAN (Oryctolagus cuniculus)
Green tea leaf extract at 7.5% concentration effectively promotes hair growth, similar to minoxidil.
research Khảo sát đặc điểm thực vật và phân tích sơ bộ thành phần hóa thực vật của cây nắp ấm (Nepenthes kampotiana lecomte, họ nắp ấm nepenthaceae)
Nepenthes kampotiana has unique plant features and contains various beneficial compounds.
research Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study
The inhibitor affects androgen metabolism but not ovarian function.
research Anti‐Fertility Effects of Amlodipine in Adult Male Wistar Rats
Amlodipine impairs fertility in male rats by affecting sperm and testicular structure.
research The effect of the combined drug Yuperio with bisoprolol on the dynamics of the heart with dilation of the left chambers, the development of which is due to non-compactness of the myocardium of the left ventricle
Yuperio combined with bisoprolol improves heart function in patients with dilated cardiomyopathy.
research Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.
research Antioxidants and Long Covid
Antioxidants might help manage Long Covid by addressing oxidative stress and nutrient imbalances.
research Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.
Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
research Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines
Some Korean herb extracts can reduce inflammation and are safe for skin use.
research 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine
A plant extract was found to effectively block an enzyme related to male hormone-related diseases.
research Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish
Certain substances can protect against ear damage from some antibiotics in zebrafish.
research Author reply
Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.
research Elevated Circulation Levels of an Antiangiogenic SERPIN in Patients with Diabetic Microvascular Complications Impair Wound Healing through Suppression of Wnt Signaling
High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants
TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
research Higher Levels of Hair Ethyl Glucuronide in Patients with Decreased Kidney Function
People with decreased kidney function have higher levels of ethyl glucuronide in their hair.
research Les nouvelles stratégies thérapeutiques du traumatisme sonore par bruit d'arme chez le cobaye
Magnesium and caspase inhibitors help protect hearing after gunshot noise.
research POS1171 LIVING WITH LUPUS NEPHRITIS: ELEVATED IMPACT ON PATIENT LIFE
Lupus nephritis patients face more challenges in family planning, work, symptoms, medication, and quality of life than those without it.
research Effects of Nitrendipine (BAY e 5009), Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle
Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
research Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling
Strontium zinc silicate may help treat osteoporosis and muscle loss.
research CAQ Corner: Basic concepts of transplant immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research Data mining on varieties, therapeutic uses and medicinal characteristics of Traditional Chinese Medicine preparations for treating hair loss
Traditional Chinese Medicine uses various herbal preparations to treat hair loss by focusing on kidney and liver health.
research Studies on lysosomes—XIII
Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.