August 2025 in “Dermatology and Therapy” JAK inhibitors show promise for treating alopecia areata but have serious side effects.
4 citations
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January 2025 in “Pharmaceutics” The gel is a safe and effective treatment for hyperpigmentation.
2 citations
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May 2020 in “JAAD case reports” Ruxolitinib can cause a delayed skin reaction on the nose.
January 2023 in “Indian Dermatology Online Journal” No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.
15 citations
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September 2014 in “PloS one” The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.
3 citations
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July 2023 in “International journal of molecular sciences” Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
1 citations
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December 2016 JAK inhibitors have therapeutic potential but pose significant risks, requiring careful monitoring.
February 2023 in “Journal of Ginseng Research/Journal of ginseng research” New ginseng compounds may help treat degenerative diseases.
277 citations
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December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
263 citations
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February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
219 citations
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March 2004 in “Journal of The American Academy of Dermatology” 5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
205 citations
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January 2005 in “Skin pharmacology and physiology” Liposomes and niosomes can help drugs penetrate the skin better.
202 citations
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June 2005 in “Aaps Pharmscitech” Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
188 citations
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October 2012 in “The AAPS Journal” The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
138 citations
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August 1985 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth in male pattern baldness.
133 citations
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July 2006 in “International Journal of Dermatology” The cream effectively and safely reduces facial hair in women.
132 citations
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November 1998 in “Journal of the American Academy of Dermatology” Topical sensitizers have mixed success in treating alopecia areata.
123 citations
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February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
115 citations
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January 2001 in “American journal of clinical dermatology” Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.
104 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
101 citations
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November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
101 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
99 citations
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June 2005 in “Endocrinology” Applying thyroid hormone T3 speeds up wound healing in mice.
96 citations
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December 2015 in “JAMA dermatology” Topical Ruxolitinib may safely treat severe hair loss.
95 citations
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June 2002 in “The Journal of Dermatology” Onion juice is more effective than tap water for hair re-growth in patchy alopecia areata.
91 citations
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April 2011 in “Journal of Ethnopharmacology” Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.
83 citations
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June 2017 in “Journal of the American Academy of Dermatology” Topical JAK inhibitors may help children with alopecia areata regrow hair.
80 citations
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September 1984 in “Journal of The American Academy of Dermatology” 5% minoxidil helps hair regrowth in androgenic alopecia.
80 citations
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October 1983 in “BMJ” Minoxidil helps hair regrowth in alopecia patients, with 16 having good results and no side effects.