39 citations
,
January 2012 in “International Journal of Trichology” Melatonin solution helps treat hair loss in men and women.
17 citations
,
January 2006 in “Veterinary Dermatology” Topical melatonin and brushing did not affect hair regrowth in Siberian Huskies.
July 2024 in “Journal of Investigative Dermatology” Topical melatonin may reduce skin aging by inhibiting certain cellular pathways.
April 2004 in “Inpharma Weekly” Melatonin helps hair growth in women with hair loss issues.
19 citations
,
November 2023 in “npj Regenerative Medicine” Synthetic melanin applied to skin speeds up wound healing.
1 citations
,
April 2024 in “Skin research and technology” Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
May 2024 in “International journal of molecular sciences” Melatonin cream may help prevent skin damage but its anti-aging and hair growth effects are unclear.
March 2014 in “Medicina cutánea ibero-latino-americana” Melatonin applied to the scalp helps increase hair density in people with early hair loss.
44 citations
,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
32 citations
,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
4 citations
,
August 2011 in “Aktuelle Dermatologie” Topical melatonin is a safe treatment that may reduce hair loss in people with androgenetic alopecia.
March 2026 in “International Journal of Science and Research (IJSR)” Melatonin protects skin and supports hair growth.
February 2023 in “Journal of Drugs in Dermatology” Melatonin may help improve hair growth in people with certain types of hair loss.
15 citations
,
December 2016 in “Advanced Pharmaceutical Bulletin” The new cream with N-acetyl glucosamine didn't change skin color after 8 weeks.
84 citations
,
April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
60 citations
,
February 1997 in “Journal of Dermatological Science” Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
26 citations
,
July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
August 2017 in “Journal of the Dermatology Nurses' Association” Latisse (bimatoprost 0.03%) is widely used in dermatology but the document doesn't give detailed evidence or numbers.
August 2025 in “Annals of Medicine” Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
November 2022 in “Journal of Investigative Dermatology” A new molecule was found to be a safe and effective skin lightener and anti-aging product.
126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
18 citations
,
February 2017 in “Journal of Cosmetic Dermatology” Mesotherapy for hair loss can sometimes cause more hair loss and scarring.
October 2025 in “Journal of Cosmetic Dermatology” Conventional treatments like dutasteride and minoxidil are effective for male hair loss, with some alternative treatments also showing promise.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” No cure for female pattern hair loss, but various effective treatments exist.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” Gray hair can potentially be managed or reversed with treatments that boost melanin production and address nutritional deficiencies.
March 2013 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Hormones significantly affect hair growth and loss, with potential for new treatments.
1 citations
,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
19 citations
,
May 1992 in “International Journal of Dermatology” Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.
5 citations
,
November 2015 in “Journal of Cosmetic Dermatology” Effective pain relief methods for photoepilation include topical anesthetics, cooling devices, and skin stimulation.