research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
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research Evaluation and Treatment of Gender Dysphoria to Prepare for Gender Confirmation Surgery
The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.
research Cross-sex hormone therapy in Australia: the prescription patterns of clinicians experienced in adult transgender healthcare
Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.
research Transgender and Migraine
Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.
research Androgens and Cardiovascular Disease
Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
research Infertility in Polycystic Ovary Syndrome: Focus on Low-Dose Gonadotropin Treatment
Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
research Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research 46,XY DSD due to impaired androgen production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Androgen Deprivation Therapy in Prostate Cancer: Focusing on Sexual Side Effects
Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
research Unchanged androgen-binding properties of sex hormone-binding globulin in male patients with liver cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research Contribution of androgens to chronic allograft nephropathy is mediated by dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research The Metabolism and Control Mechanism of Human Hair Follicles
Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
research Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
research Medical Options for Care of Gender Diverse and Transgender Youth
Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell
Certain drugs change freshwater snail shells to a "banana" shape.
research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients.
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Oral administration of berberine represses macrophage activation-associated benign prostatic hyperplasia: a pivotal involvement of the NF-κB
Berberine may reduce prostate enlargement by blocking inflammation.
research Novel Systematics of Nomenclature and Classification of Female Functional Androgenization (Including Polycystic Ovary Syndrome and Non-Classic Congenital Adrenal Hyperplasia)
A new system helps better diagnose and treat female androgenization conditions like PCOS.
research A Case of Familial Male-limited Precocious Puberty with a Novel Mutation
A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
research The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
research The Possibilities of Using Chromium Salts as an Agent Supporting Treatment of Polycystic Ovary Syndrome
Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
research The Case of the Elusive Androgen
The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
research Ursolic acid, a pentacyclic triterpene from Ochrosia elliptica Labill leaves and its role in the management of polycystic ovary syndrome (PCOS)
Ursolic acid from Ochrosia elliptica leaves may help manage PCOS symptoms.
research If Women Just had Their Hormones Back the Way they Were!
Balancing hormones is crucial for women's health and may require hormone therapy.
research If women just had their hormones back the way they were! (for youthful feeling-balance your hormones!)
Balancing hormones can help women feel youthful and healthy.
research Chapter 6. Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.