Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
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July 1981 in “Journal of Neuropathology & Experimental Neurology” Copper injections improved symptoms and prevented brain damage in brindled mice.
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August 2021 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” Accidental minoxidil exposure can cause serious illness or death in pets.
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
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January 1982 in “Neuroendocrinology” Dopamine affects coat color changes in agouti mice.
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November 2011 in “Development” Trps1 is essential for proper hair follicle development.
July 2023 in “Veterinary pathology” White-tailed deer can get a hair loss condition that might make them more vulnerable to environmental threats.
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March 2014 in “Cell death and differentiation” Disrupting β-catenin signaling in certain cells causes anorectal malformations.
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August 2021 in “Journal of clinical medicine” Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
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March 2003 in “The journal of small animal practice/Journal of small animal practice” Trilostane helped a dog with an adrenal tumor feel better and stay healthy.
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August 1998 in “Carcinogenesis” High levels of ODC and a mutant Ha-ras gene cause tumors in mice.
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February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
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June 2012 in “American Journal of Dermatopathology” A rare neck cyst in a 47-year-old man showed diverse skin cell types and was not linked to HPV.
June 2022 in “Veterinary evidence” Clomipramine alone does not reduce overgrooming in cats with psychogenic alopecia.
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July 2024 in “Animals” The KRTAP19-5 gene affects wool curvature in Chinese Tan sheep, with Variant B reducing curvature.
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December 2023 in “Cutis” Toluidine blue helps accurately diagnose and treat certain skin tumors in surgery.
Dual TCR Treg cells are common in mouse tissues and vary by location.
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July 2013 in “Cell Reports” Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
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January 2004 in “Journal of Investigative Dermatology” Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.
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September 2014 in “JAMA dermatology” Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.
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December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
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October 2022 in “Cell Regeneration” A new mouse model effectively mimics vitiligo for research and drug testing.
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May 2002 in “PubMed” LGD1069 effectively prevents breast tumors in mice without toxicity.
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January 2024 in “Science Advances” Touch dome keratinocytes in adult skin have traits of different skin cell types.
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March 1996 in “Proceedings of the National Academy of Sciences” CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
February 2009 in “Journal of The American Academy of Dermatology” Most patients with Tuberous sclerosis had neurological or skin issues, and over half had psychiatric problems.
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January 2015 in “Development” Hoxc8 gene helps start mammary gland development by controlling specific signals.
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August 1979 in “PubMed” Adding zinc to marmosets' water improved their health, indicating their diet lacked enough zinc.
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