research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
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research The genetics of androgenetic alopecia
Genes and hormones cause hair loss, with four genes contributing equally.
research Selective non-steroidal inhibitors of 5α-reductase type 1
Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
research Gender aspects in skin diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
research Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin
Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
research Is seborrhea a sign of autonomic impairment in Parkinson's disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research Gonadal dysgenesis and bone metabolism
Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
research Are sex discordant outcomes in COVID-19 related to sex hormones?
Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
research Hirsutism: Evaluation and treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
research Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review
Quercetin may help with PCOS symptoms, but more research is needed.
research Associations between transition‐specific stress experience, nocturnal decline in ambulatory blood pressure, and C‐reactive protein levels among transgender men
Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.
research Androgens Affect the Activity of Human Sebocytes in Culture in a Manner Dependent on the Localization of the Sebaceous Glands and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research Animal models of androgen-dependent disorders of the pilosebaceous apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
research Aromatase deficiency in a male patient - Case report and review of the literature.
A male with aromatase deficiency improved bone health with estradiol treatment.
research The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis
Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
research Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp
Minoxidil boosts enzymes that help hair growth.
research Understanding and Addressing Hair Disorders in Transgender Individuals
Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.
research Formulation and optimization of transfersome containing minoxidil and caffeine
Minoxidil and caffeine in transfersomes improve hair growth treatment.
research Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research The Effect of 5 -Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Manifestation of Hyperandrogenism in the Continuous Light Exposure-Induced PCOS Rat Model
Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
research Characteristics of flutamide action on prostatic and testicular functions in the rat
Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
research Serum lipocalin-2 as an insulin resistance marker in patients with polycystic ovary syndrome
Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.
research Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Bone density is normal in male rats treated with finasteride.
Finasteride doesn't affect bone density in male rats.
research Microneedles mediated bioinspired lipid nanocarriers for targeted treatment of alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Elevated serum androstenedione is associated with a more severe phenotype in women with polycystic ovary syndrome (PCOS)
Higher androstenedione levels in women with PCOS are linked to more severe symptoms.
research Androgenic alopecia and insulin resistance: are they really related?
There is no significant link between male pattern baldness and insulin resistance.