43 citations
,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
77 citations
,
February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
1 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
July 2025 in “Journal of Investigative Dermatology”
3 citations
,
March 2020 in “Cumhuriyet Dental Journal” Regenerative dentistry using stem cells shows promise for healing and rebuilding tissues.
November 2022 in “Journal of Investigative Dermatology” Growing dermal papilla cells in 3D improves their ability to help form new blood vessels.
19 citations
,
July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
41 citations
,
June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
1279 citations
,
November 2005 in “Nature Medicine”
417 citations
,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
35 citations
,
December 2008 in “PubMed” Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.
January 2019 in “Elsevier eBooks” Understanding stem cell environments is key to developing treatments for various diseases and injuries.
Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.
Stem cells can improve skin grafts by enhancing blood flow and hair growth.
37 citations
,
May 2016 in “Scientific Reports” Combining skin cells with fat-derived stem cells can improve hair growth.
6 citations
,
January 2019 in “Biochemical and Biophysical Research Communications” Sox13 is a useful marker for early hair follicle development but not essential for hair growth.
September 2025 in “Digital Commons - RU (Rockefeller University)” Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.
29 citations
,
February 1989 in “Journal of Cutaneous Pathology” A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.
29 citations
,
June 1998 in “Developmental Biology” More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
18 citations
,
September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
3 citations
,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
11 citations
,
June 2021 in “Frontiers in Cell and Developmental Biology” Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
1 citations
,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
158 citations
,
May 2003 in “Journal of Investigative Dermatology” Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
4 citations
,
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” G2 stem cells control calcium signaling for skin regeneration.
48 citations
,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cell-derived exosomes can help stem cells grow hair.