April 2015 in “Reactions Weekly” Finasteride toxicity information is limited, poor quality, and biased.
388 citations
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September 2000 in “Cancer” Doxil's toxicity varies with dose and schedule, and pharmacokinetic guidance can optimize dosing.
382 citations
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February 2010 in “Archives of Internal Medicine” A manufacturing error in a dietary supplement caused severe selenium poisoning, affecting many people and highlighting the need for stricter quality control.
103 citations
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January 2009 in “Carbon” Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.
97 citations
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January 2020 in “Advances in chronic kidney disease” Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
82 citations
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December 2015 in “Nanomedicine” Nanoparticle systems make cancer treatment less toxic.
79 citations
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January 1975 in “Food and Cosmetics Toxicology” The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
58 citations
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January 2003 in “Biological & Pharmaceutical Bulletin” Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
52 citations
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May 1982 in “The American journal of the medical sciences” Vitamin A toxicity likely caused the patient's high calcium levels.
38 citations
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February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
32 citations
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December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
32 citations
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January 2006 in “Liver transplantation” Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
30 citations
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January 2007 Cyclophosphamide can cause serious short-term and long-term side effects, including increased cancer risk and infertility.
28 citations
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December 2006 in “Clinical lung cancer” Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.
26 citations
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July 2005 in “Optometry and vision science” Botulinum A toxin injections may cause hair loss on the face and loss of eyelashes.
25 citations
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September 1977 in “Journal of Toxicology and Environmental Health” High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
19 citations
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March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
17 citations
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January 2021 in “Agrobiological Records” Allethrin caused harmful effects and organ damage in rats, worsening with higher doses and longer exposure.
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November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.
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December 2013 in “Chemistry Central Journal” Sunlight exposure increases drug toxicity; amber glass best for protection.
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December 1962 in “Journal of Investigative Dermatology” 12 citations
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December 1951 in “Experimental Biology and Medicine” Liver in the diet reduces cortisone acetate toxicity effects in rats.
11 citations
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July 2024 in “Cancers” Preventing and managing skin issues from cancer treatment is crucial, especially in high UV areas like Australia and New Zealand.
11 citations
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September 2022 in “World Journal of Advanced Pharmaceutical and Medical Research” Nicotiana tabacum has potential therapeutic uses but also poses toxic risks.
11 citations
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February 2002 in “European Journal of Clinical Investigation” The new platinum complexes effectively increased survival in rats with tumors, despite some reversible side effects.
10 citations
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August 2020 in “Drug metabolism and drug interactions” The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.
10 citations
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August 2002 in “British Journal of Ophthalmology” Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a good alternative.
9 citations
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January 2021 in “Strahlentherapie und Onkologie” St. John's wort skin oil may increase skin damage risk during radiotherapy.
9 citations
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December 2018 in “Cutaneous and Ocular Toxicology” Combined BRAF and MEK treatment increases rash risk but reduces other skin issues compared to BRAF alone.
7 citations
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October 2021 in “Journal of Mind and Medical Sciences” Milk powder in Romania often has unsafe levels of aluminum and other elements, posing health risks.