research ADT-G as a promising biomarker for peripheral hyperandrogenism in adult female acne
ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
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research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
research BIOLOGICAL ACTIVITY OF ANTIANDROGENS
Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
research Parathyroid hormone-related peptide and the hair cycle - is it the agonists or the antagonists that cause hair growth?
PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.
research Therapeutic Androgen Receptor Ligands
Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
research Ovarian hyperthecosis coexisting with an incidental adrenal lesion: challenges in the diagnostic approach
Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.
research Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
research Abstract 5561: 20(S)-Protopanaxadiol-aglycone downregulates full-length and ligand-independent splice variants of androgen receptor
20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.
research Agouti and Agouti-related Protein: Analogies and Contrasts
Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.
research Disease severity scoring systems in dermatology
Scoring systems help doctors assess and treat skin diseases effectively.
research Male androgenetic alopecia
Hair loss in men can be slowed or reversed with treatments like minoxidil and finasteride, but it resumes if treatment stops. It may also indicate early heart disease and obesity.
research Mucocutaneous findings in pediatric patients with bone marrow transplantation
Skin and mucous membrane issues are common in kids after bone marrow transplants, so careful monitoring is crucial.
research Mesotherapy and platelet-rich plasma for the treatment of hair loss
Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.
research Lichen planopilaris: Demographic, clinical and histopathological characteristics and treatment outcomes of 25 cases
Lichen planopilaris can be accurately diagnosed and effectively treated.
research Gebelik ve emzirme döneminde kozmesötik kullanımı
Use of cosmeceuticals during pregnancy and breastfeeding is not recommended due to insufficient safety data.
research Alopesi Areatada Stresin Rolü ve Hastaların Yaşam Kalitesinin Androgenetik Alopesi ve Sağlıklı Kontrollerle Karşılaştırılması
Stress may affect alopecia areata, but it's not a confirmed trigger.
research Trichofolliculoma on gluteal area: A unique case report
A rare benign skin nodule was found on the buttock, a unique location for this condition.
research Demographic findings of patients diagnosed with pernio and comparison of their vitamin B12, folate and ferritin levels with a control group
Patients with pernio have lower vitamin B12 and ferritin levels than healthy people.
research Evaluation of hyperandrogenemia and metabolic risk profile in women with postadolescent acne
Many women with postadolescent acne also have hormonal imbalances and are at higher risk for metabolic issues.
research Alopecia and drugs
Some medications can cause hair loss, and it's important to track when the hair loss starts after taking a new medication.
research Hair transplantation: Innovations, applications
New techniques make hair transplants look more natural.
research Tufted Folikülit: Bir Olgu Sunumu
Isotretinoin reduced inflammation in tufted hair folliculitis, but hair tufting remained.
research Diffüz Alopesili Kadınlarda "Dijital Fototrikogram" ile "Darı Ekstresi, Buğday Tohumu Yağı, L-sistin, Kalsiyum Pantotenat" Formulasyonunun Etkisinin Değerlendirilmesi
Millet extract, wheat germ oil, L-cystine, and calcium pantothenate reduced hair loss and improved hair growth in women with diffuse alopecia.
research Insulin resistance and metabolic syndrome in female androgenetic alopecia
There's no clear link between female pattern hair loss, insulin resistance, and metabolic syndrome.
research P.1.g.019 RY-023, an inverse agonist at alpha5 GABAA receptors: the influence on spatial memory and spontaneous locomotor activity
RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
research Onabotulinum toxin A used to treat trichotillomania and trigeminal trophic syndrome
Onabotulinum toxin A may help treat trichotillomania and promote hair growth.
research Androgen receptor-mediated gene activation in prostate cancer cells
Androgen receptors help prostate cancer cells grow and resist drugs.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity
CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.