research Formation of the cornified envelope
The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
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research N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research A study of the effects of physical dermabrasion combined with chemical peeling in porcine skin
Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
research Dermal papilla cells induce keratinocyte tubulogenesis in culture
Skin cells can help create early hair-like structures in lab cultures.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Cell death as an architect of adult skin stem cell niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Identification of the cell lineage at the origin of basal cell carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Histopathology of non-scarring alopecia
The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
research Targeted expression of SV40 T antigen in the hair follicle of transgenic mice produces an aberrant hair phenotype
SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
research Transcutol containing vesicles for topical delivery of minoxidil
Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
research Microimaging of hairless rat skin by magnetic resonance at 900 MHz
MRI can effectively image skin structures noninvasively.
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells (SH-MSCs) on IL-10 and TNF- α Gene Expression (In Vivo Experimental Study in Male Rats of Wistar Strains Model of Fluconazole-Induced Alopecia)
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp
The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
research KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
Removing both KLK5 and KLK7 proteins can prevent death and skin issues in Netherton syndrome.
research Adult skin acute stress responses to short‐term environmental and internal aggression from exposome factors
Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
research Hormone replacement therapy and the skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Niosomes as a propitious carrier for topical drug delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Off-Label Uses of Topical Vitamin D in Dermatology: A Systematic Review
Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.
research Histological evaluation of hair follicle due to papain's depilatory effect
Papain cream removes hair better than papain gel, causing hair follicles to widen and skin to thicken.
research Botanicals With Dermatologic Properties Derived From First Nations Healing: Part 1—Trees
Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.
research Corneodesmosin: Structure, Function and Involvement in Pathophysiology
Corneodesmosin is essential for skin and hair health, and its dysfunction can lead to skin and hair disorders.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.