76 citations
,
May 2011 in “Liver transplantation” Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.
71 citations
,
November 2013 in “Clinics in Dermatology” Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
66 citations
,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
64 citations
,
November 2012 in “EMBO reports” Lamins are vital for cell survival, organ development, and preventing premature aging.
60 citations
,
September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
59 citations
,
June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
59 citations
,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
53 citations
,
January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
49 citations
,
October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
42 citations
,
January 2018 in “Expert review of precision medicine and drug development” Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
41 citations
,
April 2010 in “Gender Medicine” The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
40 citations
,
October 2012 in “British Journal of Dermatology” Minoxidil helps regrow hair in female pattern hair loss, but more research needed for other treatments.
39 citations
,
January 2019 in “Cells” Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
39 citations
,
September 2016 in “Expert Opinion on Drug Delivery” New drug delivery methods can make natural compounds more effective and stable.
35 citations
,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
33 citations
,
January 2011 in “Elsevier eBooks” Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
31 citations
,
October 2012 in “Archives of ophthalmology” Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.
29 citations
,
December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.
28 citations
,
May 2020 in “BMC plant biology” The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.
26 citations
,
October 2012 in “Dermatologic Clinics” The document details hair transplantation techniques and innovations, highlighting Follicular Unit Transplantation as the standard and discussing the effectiveness and challenges of the procedure.
26 citations
,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
22 citations
,
September 2018 in “Medical Clinics of North America” Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
19 citations
,
September 1995 in “Food and nutrition bulletin” Leucaena leucocephala is nutritious but needs careful processing to remove toxins.
18 citations
,
January 2017 in “Dermatologic Surgery” Combining cosmetic procedures with lifestyle changes improves antiaging results.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
14 citations
,
December 2010 in “Journal of human genetics” A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
13 citations
,
August 2002 in “Dermatologic Surgery” FUE is a less invasive hair transplant method suitable for many patients, but it has limitations and may not replace traditional techniques.
11 citations
,
June 2018 in “Sexual medicine reviews” Stromal Vascular Fraction might help with male sexual dysfunction, but more research is needed to confirm its safety and effectiveness.