research Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Lead to a Severe Immunodeficiency but Normal Hair and Nail Development in Patients
Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.
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research 1351 Investigation of the molecular identity of the junctional zone in human
GATA6 is important for maintaining and differentiating cells in a key area of human skin.
research Patients with Compound Heterozygous Mutations in Forkhead Box N1 have a Severe Immunodeficiency while Maintaining Normal Skin and Hair Development
Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
research 270 A novel small compound HPH-15 antagonizes TGF-β/Smad signaling and ameliorates experimental skin fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research 397 Predictive modeling of drug response and mechanism of action in alopecia areata clinical trials
Researchers found three different ways drugs work to treat hair loss from alopecia areata and identified key factors for personalized treatment.
research Abstract 81
Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
research Abstract 82
Fetal scalp cells have more regenerative genes than adult cells, and decellularized muscle matrix is better for muscle repair than commercial alternatives.
research Characterizing the cellular diversity and molecular signatures within the hair follicle dermal stem cell lineage
Unique genes in hair follicle cells help tissue regeneration.
research 709 Synthetic developmental tissue engineering of human hair follicles
Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.
research SnapshotDx Quiz: March 2016
JAK inhibitors may help treat alopecia areata by reversing hair loss.
research Redox-directed interventions targeting skin photodamage
Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
research Molecular genetics of androgen insensitivity
Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
research Recent Advances in Hair Biology and in Treatments of Androgenetic Alopecia.
Certain growth factors regulate hair growth cycles, male hormones affect hair cycles, and drugs like Minoxidil and Finasteride can stimulate hair growth and inhibit male pattern baldness respectively.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research A molecular wound response program associated with regeneration initiation in planarians
Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
research Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells
Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
research Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle
miR-31 regulates hair growth by controlling gene expression in hair follicles.
research Epidermal patterning and induction of different hair types during mouse embryonic development
Different body areas in mice produce different hair types due to interactions between skin layers.
research Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway
BMP signaling affects hair color by interacting with the MC-1R pathway.
research Oestrogen functions in skin and skin appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Thehairless gene of the mouse: Relationship of phenotypic effects with expression profile and genotype
Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Localization of varicella-zoster virus nucleic acids and proteins in human skin
The research found that chickenpox virus spreads in skin through blood then to skin cells, while shingles virus moves from nerves to hair follicle areas before infecting skin cells.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells.
Researchers made stem cells from human hair follicle cells with better efficiency than from skin cells.
research Extraction and Detection of mRNA from Horsehair
RNA can be extracted from horsehair roots for analysis.
research MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research Male sex hormone and reduced plakoglobin jointly impair atrial conduction and cardiac sodium currents
Male hormones and reduced plakoglobin can impair heart electrical function and increase arrhythmia risk in males.