43 citations
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February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
187 citations
,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
182 citations
,
December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
125 citations
,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
82 citations
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May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
62 citations
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May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
28 citations
,
November 2020 in “Journal of Controlled Release” A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
17 citations
,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
16 citations
,
August 2014 in “Colloids and surfaces. B, Biointerfaces” Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.
15 citations
,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
10 citations
,
October 2018 in “Sexual medicine reviews” Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.
9 citations
,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
7 citations
,
June 2024 in “Communications Medicine” Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
2 citations
,
November 2012 in “InTech eBooks” The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
1 citations
,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
Exosome therapy could help hair growth but needs more research for safety and effectiveness.
May 2023 in “Current Medicinal Chemistry” Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” Angio PRP speeds up skin wound healing and reduces inflammation.
February 2026 in “Human Cell” MSC-CM can boost skin cell growth and movement, aiding skin repair.
26 citations
,
July 2023 in “International Journal of Nanomedicine” The microneedle system shows promise for non-invasive brain drug delivery.
4 citations
,
July 2023 in “Journal of Cosmetic Dermatology” Adapalene microemulsions improve drug delivery through hair follicles, enhancing acne treatment.
January 2022 in “OPAL (Open@LaTrobe) (La Trobe University)” Nanoparticles in sunscreen are generally safe as they stay on the skin's surface.
4 citations
,
July 2023 in “Colloids and surfaces. B, Biointerfaces” Dissolving microneedles show promise for treating hair loss but need more research for practical use.
4 citations
,
July 2021 in “Journal of dermatology & dermatologic surgery” Microneedling is a simple, affordable treatment that helps with scars, wrinkles, stretch marks, and hair growth by boosting collagen.
January 2026 in “Pharmaceutics” New drug delivery systems show promise in effectively treating pathological scars.
July 2025 in “International Journal of Biological Macromolecules” A new microneedle system effectively delivers finasteride to treat hair loss.
May 2025 in “Acta Biomaterialia” The new microneedle treatment effectively promotes hair growth better than minoxidil.
February 2023 in “Journal of Advanced Research” A new method using Platelet-rich Plasma (PRP) in a microneedle can promote hair regrowth more efficiently and is painless, minimally invasive, and affordable.
130 citations
,
December 2022 in “Antioxidants” Natural polysaccharides have strong antioxidant properties that help fight diseases like Alzheimer's, diabetes, and heart disease.
50 citations
,
December 2000 in “Journal of Pharmaceutical Sciences” Hair follicles significantly enhance electroosmotic transport during iontophoresis.