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The document recommends a multidisciplinary approach and experience sharing to advance facial feminization surgery as a medical field.

Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Facial feminization surgery is safe and patients are satisfied, but more detailed research is needed.

Transgender patients with hair loss need personalized treatment plans considering their unique needs.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Hair transplants help transgender patients look more like their gender identity, with different procedures for trans women and men.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Individuals with male pseudohermaphroditism often do better raised as females with early surgery.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Hormone therapy in transgender people requires careful monitoring due to potential health risks and lack of standardized test values.

Hair transplantation can help transgender patients affirm their gender identity.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Forehead reduction and orbital contouring are important for satisfactory facial feminization in transgender females, with high satisfaction and low long-term problems.

Feminizing hormone therapy increases hair counts and improves hair-related quality of life, while masculinizing therapy may reduce large terminal hairs.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Provide individualized, supportive care for transgender and non-binary adolescents to improve their well-being.

The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.

Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.