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A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

Researchers created a new mouse model for studying scleroderma.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Mrp3 may aid in wound healing and hair growth.

The Apc gene is crucial for normal skin and thymus development.

The vitamin D receptor is essential for normal hair growth, even without its usual binding.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

Sebaceous glands can form new hair follicles when activated, but hair follicle bulges cannot.

Transgender treatment includes hormones and surgery, but long-term effects are unknown and counseling is needed.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Denying transgender minors gender-affirming care, while allowing it for cisgender minors, is sex discrimination.

Alopecia in transgender individuals on hormone therapy can worsen emotional distress and affect self-esteem.

Hair restoration helps transgender patients achieve desired gender appearances.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

Hair transplantation is important for transgender patients to enhance their masculine or feminine appearance.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Gender-affirming care greatly improves mental health for transgender and non-binary individuals.

Improved access to hair removal is crucial for transgender individuals before feminizing surgeries.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

The document concludes that careful planning and execution of facial gender affirmation surgery after at least 12 months of hormonal therapy can improve the quality of life for transgender individuals.

This special edition focuses on the unique aspects of treating skin conditions in women, including during pregnancy and in diverse populations like women of color and transgender patients.

Facial gender surgery techniques focus on forehead and hairline changes for accurate results.

Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.

Ornithine decarboxylase is crucial for hair growth regulation in mice.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.