222 citations
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August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
36 citations
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October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
7 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
4 citations
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January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
180 citations
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January 2011 in “EMBO Reports” A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
52 citations
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February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
19 citations
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August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
34 citations
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January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
15 citations
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November 2020 in “Development” Stem cells in the eye have different roles and behaviors, helping maintain and repair the eye's surface.
1 citations
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October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
31 citations
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August 2000 in “Journal of Investigative Dermatology” Stem cells are key for hair follicle recovery.
24 citations
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September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
7 citations
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February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
4 citations
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September 2016 in “PubMed” Using platelet-rich fibrin matrix with hair transplant techniques helps in hair regrowth in male baldness patients.
415 citations
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January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
315 citations
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June 2001 in “Nature Genetics” 90 citations
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
33 citations
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December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
23 citations
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May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
18 citations
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August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
9 citations
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June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
6 citations
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November 2023 in “Stem Cell Reports” Stem cells in the cornea show unexpected flexibility and have important implications for medicine.
3 citations
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January 2020
101 citations
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March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
67 citations
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June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
9 citations
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April 2018 in “Canadian Journal of Animal Science” LEF-1 boosts cell growth in goat hair follicles, aiding cashmere production.
375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.