March 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Minoxidil treatment improves heart defects in a DiGeorge syndrome model.
17 citations
,
January 2019 in “International journal of biological sciences” Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.
October 2023 in “Cell & bioscience” A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.
16 citations
,
February 2022 in “Science Advances” Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
117 citations
,
August 1999 in “Nature Genetics” January 2013 in “Frontiers in Immunology” Parental uveitis increases offspring's risk and severity of autoimmune eye disease.
April 2026 in “Human Genome Variation” Long-read RNA sequencing can identify complex gene changes in IFAP syndrome.
6 citations
,
July 1994 in “Journal of Dermatological Science” Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.
Defective nuclear transport may cause gene expression changes in Progeria.
59 citations
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November 2011 in “Development” Trps1 is essential for proper hair follicle development.
6 citations
,
April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
4 citations
,
September 2024 in “Development” Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.
16 citations
,
February 2014 in “Journal of Investigative Dermatology” Researchers developed a mouse model that tracks hair growth using bioluminescence, improving accuracy in studying hair cycles.
July 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.
January 2006 in “OpenCommons at University of Connecticut (University of Connecticut)” Overexpressing AVP1 and AtNHX1 in plants improves salt tolerance and root hair development.
2 citations
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September 2008 in “Fertility and Sterility” Adult offspring of sperm donation generally feel positive about their conception and view the donor as their biological father.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
7 citations
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September 2019 in “Journal of Cellular Physiology” Akt2 protein is essential for normal cell division in early mouse embryos.
9 citations
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November 2019 in “Cell calcium” The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
2 citations
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July 2022 in “The Kaohsiung Journal of Medical Sciences” FTY720 helps transplanted fat survive better by reducing immune rejection and improving blood vessel growth.
8 citations
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August 2009 in “Pediatric transplantation” A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.
85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
3 citations
,
June 2002 in “Transgenic Research” Scientists made a mouse that can be made to lose hair and then grow it back.
4 citations
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September 2020 in “Stem Cell Research & Therapy” Xenobiotic-free progenitor cells improve wound healing and blood vessel formation.
38 citations
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May 1971 in “Clinical genetics” A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
5 citations
,
January 2020 in “in Vivo” Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
13 citations
,
June 2012 in “European journal of medical genetics” Identical twins had different symptoms because one had more cells with an extra chromosome fragment in different tissues.
24 citations
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January 2011 in “Sexual Development” Intersex frogs have different brain gene activity related to sex and thyroid hormones.
Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.