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Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.

REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.

Testosterone reduces key molecules needed for early pregnancy in rats.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.

Social isolation makes rats more sensitive to alcohol's effects on the brain.

Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.

Blocking certain brain processes reduces mating behavior in female rats.

5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.

Blocking testosterone action may improve breathing during NREM sleep in healthy men.

Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Suppressing ODC activity reduces tumor growth in hair follicles.

Allopregnanolone, a progesterone metabolite, helps reduce restraint effects on behavior.

Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Astressin-B can reverse and prevent hair loss in stressed mice.

Progesterone reduces anxiety without needing progesterone receptors.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

A gene mutation causes curly hair and hair loss in rats.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.