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Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Liposomes are not better than acetone for applying DHT on skin.

Cyproterone acetate with estradiol improved women's self-confidence and emotional well-being without a difference between oral or transdermal methods, but younger women preferred the oral method.

Clascoterone safely promotes hair growth similar to minoxidil.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.

Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.

Blocking testosterone speeds up wound healing in males.

Testosterone reduces key molecules needed for early pregnancy in rats.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

A woman developed male traits from accidental contact with her husband's testosterone gel.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.

Transcutol® helps drugs penetrate the skin more effectively in various formulations.

The microneedle patch with quercetin, zinc, and copper effectively promotes hair regrowth for androgenic alopecia.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Parental support and gender-affirming care are crucial for the mental health of transgender adolescents.

High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.

Clascoterone cream effectively reduces acne severity and is safe for patients 12 and older.

Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Finasteride is safe and effective for hair loss in transgender men, but may affect testosterone therapy.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.