January 2026 in “American Journal of Translational Research” The metoprolol-spironolactone combination improves heart function in patients with coronary heart disease and heart failure.
May 2020 in “Research Square (Research Square)” Bone marrow stem cells help heal intestines and reduce death in liver failure.
192 citations
,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
177 citations
,
December 2002 in “The Lancet” Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.
108 citations
,
December 2003 in “Clinical breast cancer” PLD is an effective and safer alternative for treating breast cancer.
75 citations
,
November 2009 in “Gynecological Endocrinology” Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.
75 citations
,
November 2007 in “Clinical endocrinology” Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
67 citations
,
October 2005 in “Annals of Oncology” Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
61 citations
,
March 1981 in “Circulation” Minoxidil improves blood flow in heart failure patients.
54 citations
,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
43 citations
,
August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
41 citations
,
April 2012 in “Journal of The European Academy of Dermatology and Venereology” Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.
39 citations
,
January 2019 in “Cells” Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
36 citations
,
January 2015 in “Dermatology” Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.
36 citations
,
May 2004 in “The journal of small animal practice/Journal of small animal practice” Combining cyclosporine A and ketoconazole can effectively treat anal furunculosis in dogs, with some experiencing recurrences and mild side effects.
32 citations
,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
32 citations
,
March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
31 citations
,
January 1989 in “Clinical and Experimental Dermatology” The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.
25 citations
,
March 2008 in “Surgical Neurology” New techniques for treating scalp blood vessel malformations are effective and can have good cosmetic results.
21 citations
,
September 1979 in “Archives of Otolaryngology-head & Neck Surgery” The Juri flap procedure is effective for hair transplantation but requires careful patient selection and skilled surgeons.
19 citations
,
June 2020 in “International Journal of Dermatology” Low-dose oral minoxidil effectively treats non-scarring hair loss with some side effects like hypertrichosis and postural hypotension.
17 citations
,
February 2001 in “Urologia Internationalis” Stopping alpha-blocker medication after 6-9 months is safe and effective for most patients with bladder outlet obstruction.
14 citations
,
January 2024 in “Theranostics” Intranasal delivery of gene therapy shows promise for treating ischemic stroke.
10 citations
,
May 2021 in “Expert Opinion on Drug Delivery” Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
10 citations
,
July 1981 in “Archives of Otolaryngology-head & Neck Surgery” Short scalp flaps are easier but not good for severe baldness; Juri flaps are complex but better for density and coverage.
9 citations
,
September 1947 in “Archives of dermatology and syphilology” Electrolysis is better for permanent hair removal with less scarring.
7 citations
,
March 2020 in “Lasers in Medical Science” LLLT is a safe, promising hair loss treatment, but more research needed.
7 citations
,
April 2012 in “Clinical investigation” Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
6 citations
,
July 2013 in “Acta Clinica Belgica” The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
6 citations
,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Gray hair regained color after thyroid hormone treatment.