114 citations
,
August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
71 citations
,
October 2013 in “Experimental Dermatology” Vitiligo and alopecia areata may have similar causes despite their differences.
55 citations
,
October 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
55 citations
,
August 2013 in “PloS one” Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.
49 citations
,
March 2004 in “Journal of Investigative Dermatology” The hHa7 gene is regulated by androgens in certain body hair, not scalp hair.
45 citations
,
May 2024 in “International Journal of Molecular Sciences” Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
41 citations
,
January 2018 in “Advances in experimental medicine and biology” 37 citations
,
August 2020 in “BMC Genomics” Hair greying is mainly influenced by age, with genetics playing a smaller role.
31 citations
,
July 2021 in “ImmunoTargets and therapy” Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
29 citations
,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
26 citations
,
July 2019 in “Dermatology and Therapy” The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.
21 citations
,
February 2019 in “Experimental Dermatology” Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.
21 citations
,
July 2018 in “International Journal of Molecular Sciences” Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
16 citations
,
January 2022 in “International journal of molecular sciences” Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
15 citations
,
March 2020 in “Experimental and Therapeutic Medicine” The skin is a large organ that plays a role in the immune system.
11 citations
,
October 2022 in “Clinical Cosmetic and Investigational Dermatology” Personalized skincare can be improved by understanding genetic differences and using compounds like Resveratrol and Quercetin.
9 citations
,
November 2022 in “Biology” Key genes and pathways influence wool traits in Merino sheep.
5 citations
,
February 2022 in “Acta Biomaterialia” Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
4 citations
,
November 2025 in “Nature Reviews Disease Primers” 3 citations
,
September 2025 in “Frontiers in Immunology” JAK inhibitors are effective for treating moderate-to-severe alopecia areata.
2 citations
,
May 2022 in “Cosmetics” Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.
1 citations
,
December 2023 Hair grows in cycles and changes with age, starting from fetal development.
1 citations
,
March 2023 in “Clinical, Cosmetic and Investigational Dermatology” Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.
1 citations
,
January 2021 in “Brazilian Journal of Medical and Biological Research” Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.
February 2026 in “International Journal of Molecular Sciences” PDLLA filler can improve hair thickness and shine by reducing age-related hair decline.
November 2025 in “BMC Genomics” Genetic differences in sheep affect wool type, with fat and immune genes influencing hair traits.
September 2025 in “PubMed” Mechanical stimulation and new therapies show promise for hair regrowth.
January 2025 in “British Journal of Dermatology” Long scalp hair evolved for cooling and social signaling.
January 2025 in “Molecules” Caffeine may help with hair loss, but more research is needed to confirm its effectiveness.