research Breaking the “rule-of-five” to access Bridged Bicyclic Heteroaromatic Bioisosteres
A new method creates valuable compounds for drug discovery by breaking traditional chemical rules.
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research 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Transdermal permeation of tetracaine hydrochloride by lecithin microemulsion: In vivo
Lecithin microemulsion safely delivers tetracaine hydrochloride through the skin.
research 5 Dihydrotestosterone metabolism
Certain finger length ratios and body hair patterns may predict side effects from birth control pills in women.
research Toluene Diisocyanate (TDI) Disposition and Co-Localization of Immune Cells in Hair Follicles
Toluene diisocyanate exposure can cause immune sensitization by interacting with proteins in hair follicles and sebaceous glands.
research Crystal Structure and Synthesis of 17α-Acetoxy-pregn-4,6-diene-3,20-dione
The compound was successfully made and shows potential for treating prostate cancer.
research Ion pairs of risedronate for transdermal delivery and enhanced permeation rate on hairless mouse skin
Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Treatment of frontal fibrosing alopecia: literature review 2020-2025
Frontal fibrosing alopecia can be managed with personalized combination therapies, but no cure exists yet.
research TỔNG QUAN VỀ SINH HỌC CỦA TÓC, MÔ HÌNH NGHIÊN CỨU VÀ ĐÁNH GIÁ KHẢ NĂNG MỌC LẠI TÓC TRÊN IN-VITRO VÀ IN-VIVO
Natural remedies like grapefruit and rosemary may help hair regrowth.
research Síndrome de ovarios poliquísticos Polycystic ovary syndrome
PCOS is a common condition in women that causes various symptoms and health issues, treatable with lifestyle changes and medication.
research Melatonin and hair physiology: reasons and clinical efficacy data as a topical treatment of androgenic alopecia
Melatonin applied to the scalp helps increase hair density in people with early hair loss.
research Melatonina y fisiología capilar: razones y datos de eficacia clínica como tratamiento
Melatonin applied to the scalp helps treat early-stage hair loss in men and women.
research Alopecia androgenética en varones jóvenes: un indicador clínico temprano de resistencia a la insulina
Young men with hair loss may have a higher risk of insulin resistance and related health issues.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research ADVANCES IN PSORIASIS THERAPY
New psoriasis treatments are effective but come with side effects and risks.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research A comparison of the cytotoxic effects of fatty acids on in vitro breast and prostate cell lines
DHA derivatives, especially didocosahexaenoin, effectively kill prostate cancer cells and may offer a safer cancer treatment option.
research Normalized androgen ratio: its application to clinical dermatology
The normalized androgen ratio can help manage conditions with excess androgen activity in women.
research Hair Growth Promoting and Anticancer Effects of p21-activated kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia zerumbet
Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.
research The effect of Lactobacillus plantarum hydrolysates promoting VEGF production on vascular growth and hair growth of C57BL/6 mice
Lactobacillus plantarum hydrolysates may help increase hair growth by boosting VEGF production.
research Validación de una adaptación transcultural al idioma español de la escala Hair Specific Skindex-29
The Spanish version of the Hair Specific Skindex-29 scale is a reliable and valid way to measure the impact of hair loss on women's quality of life.
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Alopecia y microbioma: ¿futura diana terapéutica?
The document concludes that changing the scalp's microbiome might be a new way to treat hair loss.
research Revisión de compositos de biocerámicas y biopolímeros mediante electrohilado para su uso potencial como andamios para la sustitución de piel
Bioceramic and biopolymer composites are promising for advanced wound care, promoting healing and cell growth.
research Alopecia androgenética e seus tratamentos alternativos: uma revisão de literatura
Individualized treatment is crucial for managing hair loss and its effects.
research Plasma rico en plaquetas como terapia autóloga en la medicina regenerativa: Revisión narrativa
El plasma rico en plaquetas puede ayudar en la regeneración celular y podría ser útil en tratamientos complementarios para enfermedades sin cura específica.
research Minoxidil tópico o minoxidil oral en la alopecia. ¿Cuál es su elección?
Choose between topical and oral minoxidil for hair growth based on personal tolerance and side effects.
research Particularidades dermatológicas, fisiológicas e as dermatoses na pele negra
Black skin has unique features and conditions, needing tailored dermatological care.
research El contexto de la tricología en el médico
Hair and scalp health needs more attention in medical training.