research Transcriptomic insights into the effects of tyrosine on sub-Columbian plumage in H line chickens
A 1.0% tyrosine diet increases melanin in chicken feathers.
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research Identification of tpo, tg, tshr and ana antibodies associated with thyroid disorders
Patients with thyroid disorders show different symptoms and antibody levels.
research Morphogenesis- and Hair Cycle-dependent Expression of Trichohyalin, Peptidylarginine Deiminase Type III and Deiminated Trichohyalin in Rat Dorsal Skin Hair Follicles
THH and PAD type III appear together early in hair growth, but deiminated THH appears later, suggesting another factor is involved.
research Repigmentation of Leukotrichia Due to Retrograde Migration of Melanocytes After Noncultured Epidermal Suspension Transplantation
The treatment improved hair color in most vitiligo patients without major side effects.
research CHEMICAL FORM OF THE IODINE PRESENT IN THE HAIR OF THE RAT
Iodine in rat hair is linked to hair growth.
research Development of a FRET-based 3D in vitro breast tumor model and its application in evaluating drug-induced apoptosis
A new 3D breast tumor model helps test drug effects more accurately than traditional methods.
research BH31 Ritlecitinib for severe alopecia areata: does regional prescribing match national guidance?
Ritlecitinib was approved for severe alopecia areata (AA) by NICE in March 2024, with additional guidance from BHNS and BAD. A retrospective audit across six regional dermatology centers assessed adherence to these guidelines. The study included 57 patients, all with severe AA, with some reclassified from moderate AA due to additional factors. The mean treatment duration was 12.6 months, and 47% had prior systemic therapy. Psychological assessments were documented in 58% of cases. After 36 weeks, 21 out of 41 patients had not achieved the desired SALT score, yet some continued treatment beyond guidelines. Most patients reported no adverse events. The audit found regional prescribing largely aligned with national guidance but highlighted the need for better psychological assessments and consistent SALT scoring to guide treatment continuation.
research 42004 Scalp, eyebrow, and eyelash hair regrowth with continued ritlecitinib treatment among patients with alopecia areata without target efficacy response at Week 24: post hoc analysis of the ALLEGRO phase 2b/3 study
Continued ritlecitinib treatment can lead to hair regrowth in some patients with alopecia areata who initially don't respond.
research NUDT15,FTO, andRUNX1genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases
Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
research Sustained Scalp, Eyebrow, and Eyelash Hair Regrowth with Ritlecitinib Through Week 48 in Patients with Alopecia Areata: Post-Hoc Analysis of the ALLEGRO Phase 2b/3 Study
Ritlecitinib effectively maintains hair regrowth in alopecia areata patients.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Efficacy and safety of the oral Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor ritlecitinib over 24 months: integrated analysis of the ALLEGRO phase IIb/III and long-term phase III clinical studies in alopecia areata
Ritlecitinib effectively treats alopecia areata and is safe for long-term use in people 12 and older.
research Synthesis of 4-amidinoimidazoles incorporating a cyanamide moiety : novel precursors for biologically important purines
research Endogenous Skin Fluorescence is a Good Marker for Objective Evaluation of Comedolysis
Fluorescence can effectively measure acne treatment progress.
research Identification and characterization of the hamster polyomavirus middle T antigen
The hamster polyomavirus middle T antigen is linked to tumors in hamsters and associates with a specific tyrosine kinase.
research A technique for more precise distinction between catagen and telogen human hair follicles ex vivo
Researchers developed a new method using methylene blue staining to more accurately identify the growth stage of human hair follicles.
research Ultrasound-Assisted Facile Synthesis and Anticancer Evaluation of Novel N-(2-substituted phenyl-4-oxathiazolidine-3-carbonothioyl) benzamide
Researchers made new compounds that could potentially be developed into anticancer drugs.
research Tardily accelerated neurologic deterioration in two-step thallium intoxication
Thallium poisoning can cause worsening nerve damage and vision loss without typical symptoms.
research STUDIES ON THE STAINING REACTION OF THE FLUORESCENT CONJUGATE OF GLOBULIN
Normal cells stain well with fluorescent globulin, but tumor cells do not.
research The effect of experimental hypothyroidism on the skin of adult male albino rats and the therapeutic role of topical triiodothyronine
Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
research 420 Severe thiopurine-induced myelotoxicity and hair loss in Japanese patients with NUDT15 gene variant: A retrospective case-control study
Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.
research Hair radioactivity as a measure of exposure to radioisotopes
Hair can measure exposure to radioisotopes.
research Tricotiodistrofia. Reporte de un caso
A 2-year-old boy was diagnosed with a rare genetic condition causing fragile hair, intellectual issues, and short stature.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
research The Role of Toluidine Blue in Mohs Micrographic Surgery: A Systematic Review
Toluidine blue helps accurately diagnose and treat certain skin tumors in surgery.
research 803 Taxane chemotherapy induces epigenetic changes and premature senescence in human scalp hair follicles
Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.
research Linkage of Monilethrix to the Trichocyte and Epithelial Keratin Gene Cluster on 12q11-q13
research Molecular mapping of lymph node metastases by real-time reverse transcription polymerase chain reaction in two melanoma patients
The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.
research Chronic Toxicity Studies of the Potential Cancer Preventive 2-(Difluoromethyl)-dl-ornithine
Lower dosages of 2-(difluoromethyl)-dl-ornithine might reduce side effects, supporting further research.